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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

B RAF

P16INK4A

P21 RAS

CBL

KRAS

RAF1

EVI1

NRAS

PIK3R5

MEK2

SHC

MDM2

MEK1

P21

ACTIVIN A RECEPTOR TYPE IC

CTBP2

IKK GAMMA

AKT1

PI 3 KINASE P85 ALPHA

SMAD3

A RAF

ACTIVIN A RECEPTOR TYPE IB

AKT2

AKT3

CDK4

NF-KB P65

PI 3 KINASE P55 GAMMA

CBLB

ERK1

IKK BETA

RUNX1

STAT5A

CDK6

RB

ERK2

P27 KIP 1

P38

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

TGF BETA 2

TGF BETA RECEPTOR II

BAD

BCL X

BCR

C ABL

CBL C

CTBP1

E2F3

GAB2

GRB2

NFKB1

PIK3CB

SHP2

TGF BETA RECEPTOR I

C-MYC

HDAC2

E2F2

IKK ALPHA

SLI

SOS2

CRKL

CYCLIN D1

E2F1

HDAC1

IKB ALPHA

PI 3 KINASE P85 BETA

PIK3CD

SHC3

SHC4

SMAD4

SOS1

STAT5B

TGF BETA 1

TGF BETA 3

MECOM

TP53

Myc-DDK

Tag Free

TurboGFP

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-AC-Myc-DDK

pCMV6-XL5

pCMV6-XL4

pCMV6-XL6

pCMV6-AC

No

Yes

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

Stem cell - Pluripotency

ES Cell Differentiation/IPS

Transmembrane

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Secreted Protein

Cancer stem cells

Phosphatase

Induced pluripotent stem cells

Adult stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Regulation of actin cytoskeleton

Focal adhesion

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Insulin signaling pathway

Endocytosis

Colorectal cancer

Calcium signaling pathway

Ubiquitin mediated proteolysis

Chemokine signaling pathway

Neurotrophin signaling pathway

Olfactory transduction

Wnt signaling pathway

Prostate cancer

Huntington's disease

Pancreatic cancer

Endometrial cancer

Tight junction

Natural killer cell mediated cytotoxicity

Progesterone-mediated oocyte maturation

Alzheimer's disease

Purine metabolism

Jak-STAT signaling pathway

Melanoma

Axon guidance

ErbB signaling pathway

Cell cycle

p53 signaling pathway

B cell receptor signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Vascular smooth muscle contraction

Fc epsilon RI signaling pathway

Glioma

GnRH signaling pathway

Apoptosis

Chronic myeloid leukemia

Melanogenesis

Adherens junction

Oocyte meiosis

mTOR signaling pathway

Small cell lung cancer

Cell adhesion molecules (CAMs)

Renal cell carcinoma

Non-small cell lung cancer

Fc gamma R-mediated phagocytosis

Gap junction

Dilated cardiomyopathy

Type II diabetes mellitus

Lysosome

VEGF signaling pathway

Toll-like receptor signaling pathway

Thyroid cancer

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Bladder cancer

Hypertrophic cardiomyopathy (HCM)

Mismatch repair

Glycolysis / Gluconeogenesis

Spliceosome

Parkinson's disease

Hematopoietic cell lineage

Pyrimidine metabolism

Oxidative phosphorylation

Systemic lupus erythematosus

Phosphatidylinositol signaling system

Adipocytokine signaling pathway

Viral myocarditis

Amino sugar and nucleotide sugar metabolism

PPAR signaling pathway

Primary immunodeficiency

Starch and sucrose metabolism

Amyotrophic lateral sclerosis (ALS)

TGF-beta signaling pathway

ECM-receptor interaction

Antigen processing and presentation

Cardiac muscle contraction

Basal cell carcinoma

NOD-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Ribosome

Homologous recombination

Glycerophospholipid metabolism

Inositol phosphate metabolism

RIG-I-like receptor signaling pathway

Complement and coagulation cascades

Vibrio cholerae infection

Notch signaling pathway

Pathogenic Escherichia coli infection

Galactose metabolism

Drug metabolism - cytochrome P450

Maturity onset diabetes of the young

Metabolism of xenobiotics by cytochrome P450

Dorso-ventral axis formation

RNA degradation

Cytosolic DNA-sensing pathway

Arginine and proline metabolism

Taste transduction

Hedgehog signaling pathway

Arachidonic acid metabolism

Glutathione metabolism

Drug metabolism - other enzymes

Retinol metabolism

Valine

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Pyruvate metabolism

Glycerolipid metabolism

Fatty acid metabolism

Lysine degradation

Autoimmune thyroid disease

Proteasome

Citrate cycle (TCA cycle)

leucine and isoleucine degradation

Base excision repair

Sphingolipid metabolism

ABC transporters

Prion diseases

Type I diabetes mellitus

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

Porphyrin and chlorophyll metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

SNARE interactions in vesicular transport

Glycosphingolipid biosynthesis - lacto and neolacto series

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Allograft rejection

Ether lipid metabolism

Basal transcription factors

Histidine metabolism

Selenoamino acid metabolism

Glycine

serine and threonine metabolism

Pentose phosphate pathway

Butanoate metabolism

Nitrogen metabolism

Regulation of autophagy

RNA polymerase

Phenylalanine metabolism

Glycosaminoglycan degradation

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

O-Glycan biosynthesis

Linoleic acid metabolism

Pentose and glucuronate interconversions

Asthma

Nicotinate and nicotinamide metabolism

Keratan sulfate biosynthesis

One carbon pool by folate

beta-Alanine metabolism

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Heparan sulfate biosynthesis

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Primary bile acid biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Terpenoid backbone biosynthesis

Renin-angiotensin system

Glyoxylate and dicarboxylate metabolism

Non-homologous end-joining

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Circadian rhythm - mammal

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

Protein export

leucine and isoleucine biosynthesis

Folate biosynthesis

Thiamine metabolism

C21-Steroid hormone metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Fatty acid biosynthesis

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

O-Mannosyl glycan biosynthesis

D-Glutamine and D-glutamate metabolism

Vitamin B6 metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

1

Yes

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