United States
Germany
Japan
United Kingdom
China
CBLB (NM_170662) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC206047L3V
- LentiORF®
-
Lenti ORF particles, CBLB (Myc-DDK tagged) - Human Cas-Br-M (murine) ecotropic retroviral transforming sequence b (CBLB), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
货期*
详询
规格
Product images
经常一起买 (3)
热销推荐Specifications
| Product Data | |
| Product Name | CBLB (NM_170662) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | Cbl-b; Nbla00127; RNF56 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_170662 |
| ORF Size | 2946 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC206047).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_170662.3 |
| RefSeq Size | 3976 bp |
| RefSeq ORF | 2949 bp |
| Locus ID | 868 |
| Protein Families | Druggable Genome |
| Protein Pathways | Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis |
| MW | 109.4 kDa |
| Gene Summary | This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
