ARF1 Mouse Monoclonal Antibody [Clone ID: AT1B3]

Specifications

Product Data
Clone Name	AT1B3
Applications	ELISA, FC, IF, WB
Recommend Dilution	ELISA. Western blot (1/1000). Flow Cytometry. Immunofluorescence.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human ARF1 (1-181aa) purified from E. coli
Specificity	The antibody recognizes Human ARF1. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ADP ribosylation factor 1
Database Link	Entrez Gene 375 Human UniProt ID P84077
Background	ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family member is essential and ubiquitous in eukaryotes, being involved in vesicular transport and functioning as an activator of phospholipase D and cholera toxin. The functions of ARF proteins in membrane traffic and organelle integrity are intimately tied to its reversible association with membranes and specific interactions with membrane phospholipids. ARF1 is various membrane trafficking events in the ER-Golgi system and in the maintenance of organelle structure. Inactive ARF1 (ARF1-GDP) localizes in the cytoplasm, while the active form (ARF1-GTP) localizes in the membrane.
Synonyms	ADP-ribosylation factor 1
Reference Data
Protein Pathways	Vibrio cholerae infection

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