pMirTarget 3' UTR Assay Vector

CAT＃: PS100062

pMirTarget, the cloning vector for all 3' UTR clones for miRNA target validation, 10ug

Datasheet
SDS
Vector Sequence

CNY 5,420.00

货期*
现货
规格
    • 10 ug
Cited in 122 publications.

Product images

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Specifications

Product Data
sds_url /sds/ps100062.pdf
_pt 1
expression Mammalian
_c 3-utr-assay-vector
availabilities_filter In Stock
sub_category 3' UTR Assay Vector
ecoli_selection Kanamycin (25 ug/mL)
fpfeature Green, dimer
multiple_cloning /assets/images/trueorf/ps100062-mcs.gif
description pMirTarget, the cloning vector for all 3' UTR clones for miRNA target validation, 10ug
pdf_url /datasheet/ps100062.pdf
product_name pMirTarget 3' UTR Assay Vector
features

pMirTarget is a reporter construct with firefly luciferase as a reporter. The multiple cloning sites are downstream of luciferase stop codon and allow insertion of any sequence of interest, creating a chimerical transcript. All of OriGene’s 3' UTR clones are constructed in this vector. In the presence of appropriate miRNA (external or internal), shRNA or siRNA, the RNAi machinery would interact with the 3’UTR sequence and causes reduction of the luciferase activity.

  • High sensitivity of Luciferase assay due to IRES-driven luciferase cassette
  • RFP as a reporter for transfection monitoring and normalization
  • Neomycin selection marker for stable cell establishment
  • Compatible with Precision shuttling system
  • Can serve as a control for target validation experiments.
  • 3' UTR Clones for MicroRNA target validation
  • LUC_F Primer can be used to sequence the target sequence after cloning.
cell_selection Neomycin
citations Yes
vector_seq_file assets/documents/trueorf/ps100062.doc
terms LUCIFERASE; PCMV
name pMirTarget
vector Destination Vector
category Vectors
sizes_filter 10 ug
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (122)

The use of this Vectors has been cited in the following citations:
ZFP36-mediated mRNA decay regulates metabolism ,null, Cell reports ,PubMed ID 37086408
miR-145-5p Targets Sp1 in Non-Small Cell Lung Cancer Cells and Links to BMI1 Induced Pemetrexed Resistance and Epithelial–Mesenchymal Transition ,null, International Journal of Molecular Sciences ,PubMed ID 36499676
Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology ,null, mBio ,PubMed ID 35229638
Identification of the toxic 6mer seed consensus for human cancer cells ,null, Scientific Reports ,PubMed ID 35332222
Potential Anti-Metastatic Role of the Novel miR-CT3 in Tumor Angiogenesis and Osteosarcoma Invasion ,null, International Journal of Molecular Sciences ,PubMed ID 35054891
miRNA-200c-3p targets talin-1 to regulate integrin-mediated cell adhesion ,null, Scientific Reports ,PubMed ID 34732818
Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage ,null, Nature Communications ,PubMed ID 34795259
Aberrantly reduced expression of miR-342-5p contributes to CCND1-associated chronic myeloid leukemia progression and imatinib resistance ,null, Cell Death & Disease ,PubMed ID 34611140
miRNA-148a Enhances the Treatment Response of Patients with Rectal Cancer to Chemoradiation and Promotes Apoptosis by Directly Targeting c-Met ,null, Biomedicines ,PubMed ID 34680492
Knockdown of lncRNA NUTM2A-AS1 inhibits lung adenocarcinoma cell viability by regulating the miR-590-5p/METTL3 axis ,null, Oncology Letters ,PubMed ID 34630705
MiR-15a-5p Confers Chemoresistance in Acute Myeloid Leukemia by Inhibiting Autophagy Induced by Daunorubicin ,null, International Journal of Molecular Sciences ,PubMed ID 34068078
MiR-15a-5p Confers Chemoresistance in Acute Myeloid Leukemia by Inhibiting Autophagy Induced by Daunorubicin ,Bollaert, E;Claus, M;Vandewalle, V;Lenglez, S;Essaghir, A;Demoulin, J;Havelange, V;, International Journal of Molecular Sciences ,PubMed ID 34068624 [pMirTarget]
Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity ,Fernández-Tussy, P;Rodríguez-Agudo, R;Fernández-Ramos, D;Barbier-Torres, L;Zubiete-Franco, I;Davalillo, SL;Herraez, E;Goikoetxea-Usandizaga, N;Lachiondo-Ortega, S;Simón, J;Lopitz-Otsoa, F;Juan, VG;McCain, MV;Perugorria, MJ;Mabe, J;Navasa, N;Rodrigues, CMP;Fabregat, I;Boix, L;Sapena, V;Anguita, J;Lu, SC;Mato, JM;Banales, JM;Villa, E;Reeves, HL;Bruix, J;Reig, M;Marin, JJG;Delgado, TC;Martínez-Chantar, ML;, Cell death & disease ,PubMed ID 34050139 [pMirTarget]
Hypoxia-inducible factor-1α-dependent induction of miR122 enhances hepatic ischemia tolerance ,Ju, C;Wang, M;Tak, E;Kim, B;Emontzpohl, C;Yang, Y;Yuan, X;Kutay, H;Liang, Y;Hall, DR;Dar, WA;Bynon, JS;Carmeliet, P;Ghoshal, K;Eltzschig, HK;, The Journal of clinical investigation ,PubMed ID 33792566 [pMirTarget]
Circulating miR-320a Acts as a Tumor Suppressor and Prognostic Factor in Non-small Cell Lung Cancer ,null, Frontiers in Oncology ,PubMed ID 33833996
BCDIN3D RNA methyltransferase stimulates Aldolase C expression and glycolysis through let-7 microRNA in breast cancer cells ,Reinsborough, CW;Ipas, H;Abell, NS;Gouws, EB;Williams, JP;Mercado, M;Van Den Berg, C;Xhemal?e, B;, Oncogene ,PubMed ID 33664453 [pMirTarget]
Erb-B2 Receptor Tyrosine Kinase 2 is negatively regulated by the p53-responsive microRNA-3184-5p in cervical cancer cells ,null, Oncology Reports ,PubMed ID 33416166
Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation ,null, Cell Death and Differentiation ,PubMed ID 33230261
The microRNAs miR-302d and miR-93 inhibit TGFB-mediated EMT and VEGFA secretion from ARPE-19 cells ,Fuchs, HR;Meister, R;Lotke, R;Framme, C;, Exp. Eye Res. ,PubMed ID 32980316 [pMirTarget]
Long noncoding RNA MEG3 blocks telomerase activity in human liver cancer stem cells epigenetically ,Jiang, X;wang, L;xie, s;Chen, Y;Song, S;Lu, Y;Lu, D;, Research Square [pMirTarget]
Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells ,null, Scientific Reports ,PubMed ID 32641757
HMGA1-pseudogene7 transgenic mice develop B cell lymphomas ,De Martino, M;De Biase, D;Forzati, F;Credendino, SC;Palma, G;Barbieri, A;Arra, C;Paciello, O;Gaudio, E;Ponzoni, M;Vita, G;Chieffi, P;Bertoni, F;Fusco, A;Esposito, F;, Sci Rep ,PubMed ID 32341372 [pMirTarget]
MicroRNA-548-3p overexpression inhibits proliferation, migration, and invasion in osteoblast-like cells by targeting STAT1 and MAFB ,Ramírez-Salazar, EG;Almeraya, EV;López-Perez, TV;Patiño, N;Salmeron, J;Velázquez-Cruz, R;, J. Biochem. ,PubMed ID 32196088 [pMirTarget]
Circulating microRNA-590-5p functions as a liquid biopsy marker in non-small cell lung cancer ,Khandelwal, A;Seam, RK;Gupta, M;Rana, MK;Prakash, H;Vasquez, KM;Jain, A;, Cancer Sci. ,PubMed ID 31520555 [pMirTarget]
The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b ,Chaudhuri, E;Dash, S;Balasubramaniam, M;Padron, A;Holland, J;Sowd, G;Villalta, F;Engelman, AN;Pandhare, J;Dash, C;, J. Biol. Chem. ,PubMed ID 32152226 [pMirTarget]
Activation of CB2R with AM1241 ameliorates neurodegeneration via the Xist/miR-133b-3p/Pitx3 axis ,He, X;Yang, L;Huang, R;Lin, L;Shen, Y;Cheng, L;Jin, L;Wang, S;Zhu, R;, J. Cell. Physiol. ,PubMed ID 31989652 [pMirTarget]
MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro-2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt/GSK-3β pathway ,Li, B;Huang, Z;Meng, J;Yu, W;Yang, H;, Mol. Cell. Probes ,PubMed ID 31877332 [pMirTarget]
Profiling microRNAs through development of the parasitic nematode Haemonchus identifies nematode-specific miRNAs that suppress larval development ,Marks, ND;Winter, AD;Gu, HY;Maitland, K;Gillan, V;Ambroz, M;Martinelli, A;Laing, R;MacLellan, R;Towne, J;Roberts, B;Hanks, E;Devaney, E;Britton, C;, Sci Rep ,PubMed ID 31772378 [pMirTarget]
miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma ,Chava, S;Reynolds, PC;Pathania, AS;Gorantla, S;Poluektova, LY;Coulter, DW;Gupta, SC;Pandey, MK;Challagundla, KB;, Mol Oncol ,PubMed ID 31637848 [pMirTarget]
Inhibition of miR30a-3p by sulforaphane enhances gap junction intercellular communication in pancreatic cancer ,Georgikou, C;Yin, L;Gladkich, J;Xiao, X;Sticht, C;Torre, C;Gretz, N;Gross, W;Schäfer, M;Karakhanova, S;Herr, I;, Cancer Letters ,PubMed ID 31678166 [pMirTarget]
MicroRNA-193a Downregulates HMGB1 to Alleviate Diabetic Neuropathic Pain in a Mouse Model. ,null, Neuroimmunomodulation ,PubMed ID 31665716
miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling ,Wang, Q;Yu, X;Dou, L;Huang, X;Zhu, K;Guo, J;Yan, M;Wang, S;Man, Y;Tang, W;Shen, T;Li, J;, Oxidative Medicine and Cellular Longevity ,PubMed ID 31612078 [pMirTarget]
Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling ,Yuan, Z;Petree, JR;Lee, FE;Fan, X;Salaita, K;Guidot, DM;Sadikot, RT;, Cell Death Dis ,PubMed ID 31371699 [pMirTarget]
HuR interacts with lincBRN1a and lincBRN1b during neuronal stem cells differentiation ,Carelli, S;Giallongo, T;Rey, F;Latorre, E;Bordoni, M;Mazzucchelli, S;Gorio, MC;Pansarasa, O;Provenzani, A;Cereda, C;Di Giulio, AM;, RNA Biol ,PubMed ID 31345103 [pMirTarget]
Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis ,null, Proceedings of the National Academy of Sciences of the United States of America ,PubMed ID 31213543
Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells ,null, Scientific Reports ,PubMed ID 31189969
miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A ,null, Journal of Experimental & Clinical Cancer Research : CR ,PubMed ID 31227006
Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer ,Fletcher, CE;Sulpice, E;Combe, S;Shibakawa, A;Leach, DA;Hamilton, MP;Chrysostomou, SL;Sharp, A;Welti, J;Yuan, W;Dart, DA;Knight, E;Ning, J;Francis, JC;Kounatidou, EE;Gaughan, L;Swain, A;Lupold, SE;de Bono, JS;McGuire, SE;Gidrol, X;Bevan, CL;, Oncogene ,PubMed ID 31043708 [pMirTarget]
24R,25-Dihydroxyvitamin D3 regulates breast cancer cells in vitro and in vivo ,Verma, A;Cohen, DJ;Schwartz, N;Muktipaty, C;Koblinski, J;Boyan, BD;Schwartz, Z;, Biochim Biophys Acta Gen Subj ,PubMed ID 31125679 [pMirTarget]
MicroRNA-365a-3p inhibits c-Rel-mediated NF-κB signaling and the progression of pancreatic cancer ,Yin, L;Xiao, X;Georgikou, C;Yin, Y;Liu, L;Karakhanova, S;Luo, Y;Gladkich, J;Fellenberg, J;Sticht, C;Gretz, N;Gross, W;Herr, I;, Cancer Lett. ,PubMed ID 30910589 [pMirTarget]
Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells ,Yasukochi, A;Kawakubo-Yasukochi, T;Morioka, M;Hazekawa, M;Nishinakagawa, T;Ono, K;Nakashima, M;Nakamura, S;, J. Biochem. ,PubMed ID 30918974 [pMirTarget]
TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p ,null, Cancer Cell International ,PubMed ID 30976199
miR‐1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries ,null, The Journal of Physiology ,PubMed ID 29717493
Sevoflurane exerts protective effects on liver ischemia/reperfusion injury by regulating NFKB3 expression via miR-9-5p ,null, Experimental and Therapeutic Medicine ,PubMed ID 30906455
MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats ,Lv, B;Cheng, X;Sharp, FR;Ander, BP;Liu, DZ;, Front Neurosci ,PubMed ID 30405345 [pMirTarget]
Characterisation of infection associated microRNA and protein cargo in extracellular vesicles of Theileria annulata infected leukocytes ,Gillan, V;Simpson, DM;Kinnaird, J;Maitland, K;Shiels, B;Devaney, E;, Cell. Microbiol. ,PubMed ID 30370674 [pMirTarget]
A miR-125b/CSF1-CX3CL1/tumor-associated macrophage recruitment axis controls testicular germ cell tumor growth ,null, Cell Death & Disease ,PubMed ID 30237497
MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression. ,null, Biochemical pharmacology ,PubMed ID 30098313
MiR-335-5p restores cisplatin sensitivity in ovarian cancer cells through targeting BCL2L2 ,Liu, R;Guo, H;Lu, S;, Cancer Med ,PubMed ID 30019389 [pMirTarget]
MiR-126-3p inhibits ovarian cancer proliferation and invasion via targeting PLXNB2 ,Xiang, G;Cheng, Y;, Reprod Biol ,PubMed ID 30054097 [pMirTarget]
Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling ,Xin, X;Wang, C;Lin, Z;Xu, J;Lu, Y;Meng, Q;Li, X;Yang, Y;Zheng, Q;Gui, X;Li, T;Pu, H;Xiong, W;Li, J;Jia, S;Lu, D;, Mol Ther Nucleic Acids ,PubMed ID 29858072 [pMirTarget]
Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a ,Xin, X;Wu, M;Meng, Q;Wang, C;Lu, Y;Yang, Y;Li, X;Zheng, Q;Pu, H;Gui, X;Li, T;Li, J;Jia, S;Lu, D;, Mol. Cancer ,PubMed ID 29895332 [pMirTarget]
MicroRNA-204-3p inhibits lipopolysaccharide-induced cytokines in familial Mediterranean fever via the phosphoinositide 3-kinase γ pathway. ,null, Rheumatology (Oxford, England) ,PubMed ID 29294109
The E3 ligase for metastasis associated 1 protein, TRIM25, is targeted by microRNA-873 in hepatocellular carcinoma. ,null, Experimental cell research ,PubMed ID 29654742
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 ,null, American Journal of Physiology - Lung Cellular and Molecular Physiology ,PubMed ID 29167124
Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1 ,null, Oncogenesis ,PubMed ID 29396433
microRNA-181a Downregulates Deptor for TGFβ-induced Glomerular Mesangial Cell Hypertrophy and Matrix Protein Expression ,null, Experimental cell research ,PubMed ID 29397070
Regulation of the Human Fc-Neonatal Receptor alpha-Chain Gene FCGRT by MicroRNA-3181 ,Ferguson, DC;Blanco, JG;, Pharm. Res. ,PubMed ID 29302759 [pMirTarget]
miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1 ,null, Clinical & Translational Oncology ,PubMed ID 29374351
MicroRNA-135a regulates NHE9 to inhibit proliferation and migration of glioblastoma cells ,null, Cell Communication and Signaling : CCS ,PubMed ID 29268774
NFE2L2/NRF2 silencing-inducible miR-206 targets c-MET/EGFR and suppresses BCRP/ABCG2 in cancer cells ,null, Oncotarget ,PubMed ID 29291022
MicroRNA-182 targets protein phosphatase 1 regulatory inhibitor subunit 1C in glioblastoma ,null, Oncotarget ,PubMed ID 29383111
Dual Role of MiR-21-Mediated Signaling in HUVECs and Rat Surgical Flap under Normoxia and Hypoxia Condition ,null, International Journal of Molecular Sciences ,PubMed ID 28880208
MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology ,null, Nature Communications ,PubMed ID 28955034
Differential expression of microRNA let-7b-5p regulates burn-induced hyperglycemia ,null, Oncotarget ,PubMed ID 29069833
Conditional Disruption of miR17∼92 in Osteoclasts Led to Activation of Osteoclasts and Loss of Trabecular Bone In Part Through Suppression of the miR17-Mediated Downregulation of Protein-Tyrosine Phosphatase-oc in Mice† ,Lau, KW;Stiffel, V;Rundle, CH;Amoui, M;Tapia, J;White, TD;Sheng, MH;, JBMR Plus [pMirTarget]
Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b ,null, eNeuro ,PubMed ID 28828398
MicroRNA-136 inhibits colon cancer cell proliferation and invasion through targeting liver receptor homolog-1/Wnt signaling. ,null, Gene ,PubMed ID 28710032
miR-193a-3p is a key tumor suppressor in ulcerative colitis-associated colon cancer and promotes carcinogenesis through up-regulation of IL17RD ,null, Clinical cancer research : an official journal of the American Association for Cancer Research ,PubMed ID 28600480
Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity ,null, British Journal of Cancer ,PubMed ID 28449010
Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1 ,Hsu, YL;Hung, JY;Chang, WA;Lin, YS;Pan, YC;Tsai, PH;Wu, CY;Kuo, PL;, Oncogene ,PubMed ID 28436951 [pMirTarget]
Angiogenesis-targeting microbubbles combined with ultrasound-mediated gene therapy in brain tumors ,Chang, EL;Ting, CY;Hsu, PH;Lin, YC;Liao, EC;Huang, CY;Chang, YC;Chan, HL;Chiang, CS;Liu, HL;Wei, KC;Fan, CH;Yeh, CK;, J Control Release ,PubMed ID 28408200 [pMirTarget]
Identification of novel fibrosis modifiers by in vivo siRNA silencing ,Vollmann, EH;Cao, L;Amatucci, A;Reynolds, T;Hamann, S;Dalkilic-Liddle, I;Cameron, TO;Hossbach, M;Kauffman, KJ;Mir, FF;Anderson, DG;Novobrantseva, T;Koteliansky, V;Kisseleva, T;Brenner, D;eld, JD;Burkly, LC;, olecular Therapy: Nucleic Acids [pMirTarget]
miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration ,null, Scientific Reports ,PubMed ID 28276476
MicroRNA106a Regulates Matrix Metalloprotease 9 in a Sirtuin Dependent Mechanism ,Edatt, L;Maurya, AK;Raji, G;K, H;Kumar, SV;, J. Cell. Physiol ,PubMed ID 28233301 [pmirTARGET]
Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis. ,null, Biochimica et biophysica acta. Molecular cell research ,PubMed ID 28088550
Calmodulin Regulated Spectrin Associated Protein 1 mRNA is Directly Regulated by miR-126 in Primary Human Osteoblasts ,Strassburg, S;Nabar, N;Lampert, F;Goerke, SM;Pfeifer, D;Finkenzeller, G;Stark, GB;Simunovic, F;, J. Cell. Biochem ,PubMed ID 27958650 [pMirTarget]
Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors ,Wielgos, ME;Rajbhandari, R;Cooper, TS;Wei, S;Nozell, S;Yang, ES;, Mol. Cancer Res ,PubMed ID 28031413 [pMirTarget]
MicroRNA-891b is an independent prognostic factor of pancreatic cancer by targeting Cbl-b to suppress the growth of pancreatic cancer cells ,null, Oncotarget ,PubMed ID 27494897
MiRNA-3978 regulates peritoneal gastric cancer metastasis by targeting legumain ,null, Oncotarget ,PubMed ID 27793040
MicroRNA-153 inhibits tumor progression in esophageal squamous cell carcinoma by targeting SNAI1. ,null, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine ,PubMed ID 27739030
MicroRNA-490 regulates lung cancer metastasis by targeting poly r(C)-binding protein 1. ,null, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine ,PubMed ID 27683057
Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy ,Wang, Q;Navitskaya, S;Chakravarthy, H;Huang, C;Kady, N;Lydic, TA;Chen, YE;Yin, KJ;Powell, FL;Martin, PM;Grant, MB;Busik, JV;, EBioMedicine ,PubMed ID 27531575
Poly r(C) binding protein (PCBP) 1 is a negative regulator of thyroid carcinoma ,null, American Journal of Translational Research ,PubMed ID 27648147
miR-526b-3p functions as a tumor suppressor in colon cancer by regulating HIF-1a ,Zhang, R;Zhao, J;Xu, J;Wang, J;Jia, J;, Am J Transl Res ,PubMed ID 27398161
Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and −186 expression: Novel mechanism of VEGF modulation in prostate cancer ,null, Oncotarget ,PubMed ID 27322147
Loss of miR-26a-5p promotes proliferation, migration, and invasion in prostate cancer through negatively regulating SERBP1. ,null, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine ,PubMed ID 27449037
Rare FOXC1 variants in congenital glaucoma: identification of translation regulatory sequences ,Medina-Trillo, C;Aroca-Aguilar, JD;Méndez-Hernández, CD;Morales, L;García-Antón, M;García-Feijoo, J;Escribano, J;, Eur. J. Hum. Genet. ,PubMed ID 26220699 [pMirTarget]
Glucocorticoid receptor beta increases migration of human bladder cancer cells ,null, Oncotarget ,PubMed ID 27036026
Dynamic regulation of uncoupling protein 2 expression by microRNA-214 in hepatocellular carcinoma ,null, Bioscience Reports ,PubMed ID 27129291
Functional characterization of eight rare missense CYP1B1 variants involved in congenital glaucoma and their association with null genotypes ,Medina-Trillo, C;Ferre-Fernández, JJ;Aroca-Aguilar, JD;Bonet-Fernández, JM;Escribano, J;, Acta Ophthalmol ,PubMed ID 27060699
Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR-30c in breast cancer ,Yen, MC;Shih, YC;Hsu, YL;Lin, ES;, Oncology reports ,PubMed ID 26707189 [PS100062]
Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC ,Taylor, MA;Wappett, M;Delpuech, O;Brown, H;Chresta, CM;, Oncogene ,PubMed ID 26776158 [PS100062]
Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated GDNF-Plasmid Delivery for Treatment of Parkinson's Disease ,Fan, CH;Ting, CY;Lin, CY;Chan, HL;Chang, YC;Chen, YY;Liu, HL;Yeh, CK;, Sci Rep ,PubMed ID 26786201 [PS100062]
Translational Regulation of the Mitochondrial Genome Following Redistribution of Mitochondrial MicroRNA (MitomiR) in the Diabetic Heart ,null, Circulation. Cardiovascular genetics ,PubMed ID 26377859
The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells ,null, Oncotarget ,PubMed ID 26036258
MicroRNA-26a inhibits TGF-β-induced extracellular matrix protein expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy. ,null, Diabetologia ,PubMed ID 26063197
ErbB2-intronic microRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signaling ,Schmitt, DC;Madeira da Silva, L;Zhang, W;Liu, Z;Arora, R;Lim, S;Schuler, AM;McClellan, S;Andrews, JF;Kahn, AG;Zhou, M;Ahn, EY;Tan, M;, Cell Death Dis ,PubMed ID 25950472 [PS100062]
A novel member of the let-7 microRNA family is associated with developmental transitions in filarial nematode parasites ,Winter, AD;Gillan, V;Maitland, K;Emes, RD;Roberts, B;McCormack, G;Weir, W;Protasio, AV;Holroyd, N;Berriman, M;Britton, C;Devaney, E;, BMC Genomics ,PubMed ID 25896062 [PS100062]
Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma ,null, Oncotarget ,PubMed ID 25860934
Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM) ,null, Biochimica et biophysica acta ,PubMed ID 25869329
miR-1269 Promotes Metastasis and Forms a Positive Feedback Loop with TGF-β ,null, Nature communications ,PubMed ID 25872451
Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1α and post-transcriptionally by miR-214 in sickle cell disease ,null, The Biochemical journal ,PubMed ID 25876995
Hypo- and Hypermorphic FOXC1 Mutations in Dominant Glaucoma: Transactivation and Phenotypic Variability ,Medina-Trillo, C;Sánchez-Sánchez, F;Aroca-Aguilar, JD;Ferre-Fernández, JJ;Morales, L;Méndez-Hernández, CD;Blanco-Kelly, F;Ayuso, C;García-Feijoo, J;Escribano, J;, PLoS ONE ,PubMed ID 25786029 [PS100062]
MicroRNA-152 represses VEGF and TGFβ1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells ,null, Molecular Vision ,PubMed ID 25802486
HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer ,Zhu, H;Berkova, Z;Mathur, R;Sehgal, L;Khashab, T;Tao, RH;Ao, X;Feng, L;Sabichi, AL;Blechacz, B;Rashid, A;Samaniego, F;, Mol. Cancer Res. ,PubMed ID 25678597 [PS100062]
miR-126 regulates platelet-derived growth factor receptor-α expression and migration of primary human osteoblasts. ,null, Biological chemistry ,PubMed ID 25205714
Down regulation of miR-202 modulates Mxd1 and Sin3A repressor complexes to induce apoptosis of pancreatic cancer cells ,null, Cancer Biology & Therapy ,PubMed ID 25611699
MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1 ,Rajendiran, S;Parwani, AV;Hare, RJ;Dasgupta, S;Roby, RK;Vishwanatha, JK;, Mol. Cancer ,PubMed ID 25406943 [TrueClone]
Identification of miRNAs that modulate glucocerebrosidase activity in Gaucher disease cells ,Siebert, M;Westbroek, W;Chen, YC;Moaven, N;Li, Y;Velayati, A;Saraiva-Pereira, ML;Martin, SE;Sidransky, E;, RNA Biol ,PubMed ID 25584808 [GE100007]
Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease ,Batra, R;Charizanis, K;Manchanda, M;Mohan, A;Li, M;Finn, DJ;Goodwin, M;Zhang, C;Sobczak, K;Thornton, CA;Swanson, MS;, Mol. Cell ,PubMed ID 25263597 [SC400919]
MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis ,null, Carcinogenesis ,PubMed ID 24925028
MicroRNA-200b Suppresses Arsenic-transformed Cell Migration by Targeting Protein Kinase Ca and Wnt5b-Protein Kinase Ca Positive Feedback Loop and Inhibiting Rac1 Activation ,Wang, Z;Humphries, B;Xiao, H;Jiang, Y;Yang, C;, J. Biol. Chem. ,PubMed ID 24841200 [BCRT101]
FMRP regulates miR196a-mediated repression of HOXB8 via interaction with the AGO2 MID domain. ,null, Molecular bioSystems ,PubMed ID 24727796
MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells ,null, American Journal of Physiology - Heart and Circulatory Physiology ,PubMed ID 24486510
The miR-106b∼25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300 ,null, Cell Death and Differentiation ,PubMed ID 24270410
MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A ,null, Oncogene ,PubMed ID 23770851
Nucleolin Mediates MicroRNA-directed CSF-1 mRNA Deadenylation but Increases Translation of CSF-1 mRNA * ,null, Molecular & Cellular Proteomics : MCP ,PubMed ID 23471483
The Role of CYP3A4 mRNA Transcript with Shortened 3?-Untranslated Region in Hepatocyte Differentiation, Liver Development, and Response to Drug Induction S⃞ ,null, Molecular Pharmacology ,PubMed ID 21998292
MicroRNAs Differentially Regulate Carbonyl Reductase 1 (CBR1) Gene Expression Dependent on the Allele Status of the Common Polymorphic Variant rs9024 ,null, PLoS ONE ,PubMed ID 23133646
Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer * ,null, The Journal of Biological Chemistry ,PubMed ID 22761427
Increased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298 ,null, The American Journal of Pathology ,PubMed ID 22521303

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