Leukemia

Leukemias are a group of hematologic disorders characterized by the dysfunctional proliferation and development of leukocytes. Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL) and Chronic Myelogenous Leukemia (CML) are the 4 major subtypes of leukemia.

CD Markers in Leukemia

The CD (cluster of differentiation) markers are frequently used in differential diagnosis of leukemia. Detection of changes in CD marker expression in leukemia is critical for understand the primary mechanisms initiating these changes.

OriGene offers a range of tools to analyze CD markers including cDNA clones, antibodies, overexpression cell lysates and more. Click the buttons below for details.

CD7 CD10 CD13 CD20 CD23 CD33 CD52 CD79a CD138 CD205

Leukemia markers stained with OriGene’s Ultra Specific Antibodies

CD10 in MDA-MB-453 cell pellets stained with UM800128

CD10 in Human Kidney stained with UM800128

CD10 in SK-MEL-28 cell pellets stained with UM800127

CD10 in Mouse Kidney stained with UM800127

CD20 in Jurkat cells stained with UM800009

CD20 in Human Lymphoma tissue stained with UM800009

CD13 in Human Lymphoma tissue stained UM800165

MLF1 in Human Colon tissue stained with UM500100

Leukemia Stems cells in Acute Myeloid Leukemia (AML)

Leukemia stem cells (LSCs)play a critical role in the initiation, progression and treatment resistance in AML. Developing markers for LSCs and understanding the molecular mechanisms of LSCs is critical for developing better targeting strategies.

OriGene offers a range of tools to analyze CD markers including cDNA clones, antibodies, overexpression cell lysates and more. Click the buttons below for details.

CD34 CD38 CD123 TIM3 CD9 HDACs NF-kB HIF-1α β-catenin

Leukemia Stem Cell markers stained with OriGene’s Ultra Specific and TrueMAB Antibodies