prothymosin, alpha (PTMA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/4000. Immunohistochemistry on Frozen Sections: 1/50 (See Ref.1,2). Immunohistochemistry on Paraffin Sections: 1/100-1/1000 (See Ref.1,2).
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic Human Thymosin alpha-1,(aa 2-29) KLH conjugated
Specificity	This antibody detects Thymosin alpha 1. There was no cross reactivity obtained against Human Thymosin beta-4 and Human Thymulin.
Formulation	State: Serum State: Lyophilized serum
Reconstitution Method	Restore in aqua bidest to initial volume
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	prothymosin, alpha
Database Link	Entrez Gene 5757 Human UniProt ID P06454
Background	The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin alpha. A peptide containing 28 amino acid residues, named thymosin alpha 1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and in vivo test systems. Thymosin alpha 1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin alpha 1.
Synonyms	PTMA, TMSA, Thymosin alpha-1
Reference Data

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