PCSK9 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	Peptide ELISA: 1/1,000. Western blotting: 1/1,000.  Flow cytometry: 1/10-1/50.  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human PCSK9.
Specificity	This antibody reacts to PCSK9.
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	proprotein convertase subtilisin/kexin type 9
Database Link	Entrez Gene 255738 Human UniProt ID Q8NBP7
Background	PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Synonyms	PCSK-9, NARC1, Proprotein convertase subtilisin/kexin type 9, Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1, NARC-1
Reference Data
Protein Families	Secreted Protein

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