TTF1 (NKX2-1) Mouse Monoclonal Antibody [Clone ID: 8G7G3/1]

Specifications

Product Data
Clone Name	8G7G3/1
Applications	IHC
Recommend Dilution	IHC: 1:100 - 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NK2 homeobox 1
Database Link	NP_003308 Entrez Gene 7080 Human UniProt ID P43699
Synonyms	BCH; BHC; EBP; NK-2; NKX2.1; NKX2A; NMTC1; T; TEBP; TITF1; TTF-1; TTF1
Note	Anti-TTF-1 (Thyroid Transcription Factor 1) is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 labelling is also seen in thyroid malignancies.
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

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