Calcitonin receptor (CALCR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-CALCR antibody: synthetic peptide directed towards the C terminal of human CALCR. Synthetic peptide located within the following region: NQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEII
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52 kDa
Gene Name	calcitonin receptor
Database Link	NP_001733 Entrez Gene 799 Human UniProt ID P30988
Background	This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Synonyms	CRT; CT-R; CTR; CTR1
Note	Immunogen Sequence Homology: Human: 100%; Dog: 79%; Pig: 79%; Guinea pig: 79%; Bovine
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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