ROS1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1E6]

Specifications

Product Data
Clone Name	OTI1E6
Applications	IHC, WB
Recommend Dilution	WB 1:500-2000, IHC 1:5000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 2126-2347 of human ROS1(NP_002935) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	ROS proto-oncogene 1, receptor tyrosine kinase
Database Link	NP_002935 Entrez Gene 6098 Human UniProt ID P08922
Background	This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]
Synonyms	c-ros-1; MCF3; ROS
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane

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