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Foxn1 (NM_008238) Mouse Tagged ORF Clone
CAT＃: MG226744
- TrueORF®
Foxn1 (tGFP-tagged) - Mouse forkhead box N1 (Foxn1), (10ug)
ORF Plasmid: DDK
"NM_008238" in other vectors (4)
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CNY 7,130.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | D11Bhm185e; Fkh19; HFH-11; Hfh11; nu; nude; wh; Whn |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG226744 representing NM_008238
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTGTCGCTACTCCCTCCGCAGTCTGACGTCACACTTCCAGGCTCCACCCGACTGGAGGGCGAACCCC AAGGGGACCTCATGCAGGCTCCGGGCCTCCCAGACTCCCCTGCCCCACAGAACCATGCTAACTTCAGCTG CTCGTCGTTTGTGCCTGACGGCCCTCCAGAGAGGACACCCTCACTGCCCCCACACAGCCCCAGCATCGCA TCTCCAGACCCAGAGCAGATCCAGGGCCACTGCACAGCCGGACCCGGCCCGGGCTCCTTCCGCCTTTCTC CTTCAGAAAAGTATCCTGGCTTTGGCTTTGAGGAGGGCCCAGCAGGCAGCCCAGGGCGCTTCCTCAAGGG CAACCACATGCCTTTCCACCCCTACAAGAGGCACTTCCATGAGGACATCTTCTCTGAGGCCCAGACGGCC ATGGCACTTGATGGACACTCCTTTAAGACTCAGGGGGCACTGGAAGCCTTTGAGGAGATCCCTGTGGACA TGGGCGATGCTGAGGCCTTCCTGCCTAGCTTCCCAGCAGAGGCTTGGTGCAATAAACTCCCTTACCCCAG CCAGGAACACAACCAAATTCTGCAGGGGTCAGAGGTCAAGGTCAAGCCCCAAGCTCTGGACAGTGGTCCT GGGATGTACTGCTACCAGCCTCCCTTGCAACATATGTACTGTTCTTCTCAGCCTGCCTTCCATCAGTACT CCCCGGGTGGAGGCAGCTACCCTGTGCCCTACCTGGGCTCACCTCACTATCCCTATCAGAGGATTGCACC CCAGGCCAACGCCGAAGGTCACCAGCCACTCTTCCCAAAGCCCATCTACTCTTACAGCATCCTCATCTTC ATGGCCCTTAAGAACAGTAAGACCGGAAGCCTTCCAGTCAGTGAAATCTACAATTTCATGACGGAGCACT TCCCTTACTTCAAGACTGCTCCTGATGGCTGGAAGAATTCTGTTCGCCATAACCTGTCCCTCAACAAGTG CTTTGAGAAGGTGGAGAATAAATCCGGAAGTTCCTCTCGAAAGGGCTGTCTGTGGGCCCTCAATCCTTCC AAAATCGACAAGATGCAGGAAGAACTGCAGAAGTGGAAGAGGAAAGACCCCATTGCTGTGCGCAAAAGCA TGGCCAAACCAGAAGAGCTGGACAGCCTCATTGGAGACAAAAGGGAAAAACTGGGCTCTCCGCTGCTGGG CTGTCCACCCCCTGGGCTGGCAGGCCCAGGTCCCATCCGGCCCATGGCACCATCAGCTGGTCTTTCCCAG CCTCTGCACCCAATGCATCCAGCTCCAGGCCCCATGCCTGGCAAGAACCCCCTGCAGGACCTACTGGGTG GCCATGCTCCCTCCTGCTATGGGCAGACCTACCCACACCTTTCCCCCAGCCTGGCCCCTTCTGGACACCA GCAGCCATTGTTCCCACAGCCAGATGGGCATCTTGAGCTGCAGGCCCAGCCAGGCACCCCCCAGGACTCA CCTCTACCTGCCCACACACCACCCAGCCACGGTGCCAAGCTGATGGCTGAGCCTTCCTCAGCCAGGACCA TGCACGATACTCTACTGCCAGATGGAGACCTTGGGACTGACCTGGATGCTATCAACCCTTCTCTCACTGA CTTCGACTTCCAGGGAAATCTGTGGGAGCAGCTGAAGGATGACAGCTTGGCCCTGGACCCCCTCGTATTG GTGACCTCGTCGCCGACGTCATCCTCCATGTTGCCACCCCCACCAGCAGCCCATTGCTTCCCCCCAGGGC CTTGTCTGGCAGAAACAGGCAATGAGGCAGGTGAACTGGCACCTCCAGGCAGCGGCGGCTCCGGTGCTCT GGGAGACATGCACCTCAGCACTCTCTACTCCGCCTTTGTGGAACTGGAGTCCACGCCCTCCTCAGCAGCT GCCGGCCCTGCCGTGTACCTCAGTCCCGGCTCAAAGCCATTGGCTCTGGCT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG226744 representing NM_008238
Red=Cloning site Green=Tags(s) MVSLLPPQSDVTLPGSTRLEGEPQGDLMQAPGLPDSPAPQNHANFSCSSFVPDGPPERTPSLPPHSPSIA SPDPEQIQGHCTAGPGPGSFRLSPSEKYPGFGFEEGPAGSPGRFLKGNHMPFHPYKRHFHEDIFSEAQTA MALDGHSFKTQGALEAFEEIPVDMGDAEAFLPSFPAEAWCNKLPYPSQEHNQILQGSEVKVKPQALDSGP GMYCYQPPLQHMYCSSQPAFHQYSPGGGSYPVPYLGSPHYPYQRIAPQANAEGHQPLFPKPIYSYSILIF MALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGSSSRKGCLWALNPS KIDKMQEELQKWKRKDPIAVRKSMAKPEELDSLIGDKREKLGSPLLGCPPPGLAGPGPIRPMAPSAGLSQ PLHPMHPAPGPMPGKNPLQDLLGGHAPSCYGQTYPHLSPSLAPSGHQQPLFPQPDGHLELQAQPGTPQDS PLPAHTPPSHGAKLMAEPSSARTMHDTLLPDGDLGTDLDAINPSLTDFDFQGNLWEQLKDDSLALDPLVL VTSSPTSSSMLPPPPAAHCFPPGPCLAETGNEAGELAPPGSGGSGALGDMHLSTLYSAFVELESTPSSAA AGPAVYLSPGSKPLALA TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_008238 |
| ORF Size | 1941 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_008238.1, NP_032264.1 |
| RefSeq Size | 3273 bp |
| RefSeq ORF | 1947 bp |
| Locus ID | 15218 |
| UniProt ID | Q61575 |
| Gene Summary | The protein encoded by this gene is part of the forkhead family or "winged-helix" transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing
,Kur-Piotrowska, A;Bukowska, J;Kopcewicz, MM;Dietrich, M;Nynca, J;Slowinska, M;Gawronska-Kozak, B;,
Sci Rep
,PubMed ID 29615703
[FOXN1]
|
Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC220062 | Foxn1 (untagged) - Mouse forkhead box N1 (Foxn1), (10ug) |
CNY 8,360.00 |
|
| MR226744 | Foxn1 (Myc-DDK-tagged) - Mouse forkhead box N1 (Foxn1) |
CNY 6,460.00 |
|
| MR226744L3 | Lenti ORF clone of Foxn1 (Myc-DDK-tagged) - Mouse forkhead box N1 (Foxn1) |
CNY 8,360.00 |
|
| MR226744L4 | Lenti ORF clone of Foxn1 (mGFP-tagged) - Mouse forkhead box N1 (Foxn1) |
CNY 8,360.00 |
