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Adcy6 (NM_007405) Mouse Tagged ORF Clone
CAT＃: MG226872
- TrueORF®
Adcy6 (tGFP-tagged) - Mouse adenylate cyclase 6 (Adcy6), (10ug)
ORF Plasmid: DDK
"NM_007405" in other vectors (4)
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CNY 10,550.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | AC6; mKIAA0422 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG226872 representing NM_007405
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCATGGTTTAGTGGCCTCCTGGTTCCCAAAGTGGATGAACGGAAAACAGCTTGGGGGGAACGCAATG GGCAGAAGCGCCCACGCCACGCGAATCGAGCCAGTGGCTTCTGCGCACCTCGCTACATGAGCTGCCTCAA GAATGCGGAGCCACCCAGCCCCACTCCTGCAGCTCACACTCGGTGCCCCTGGCAGGATGAAGCCTTCATC AGGAGGGCGGGCCCGGGCAGGGGTGTGGAGCTGGGGCTGCGGTCAGTGGCCTTGGGGTTTGACGACACTG AGGTGACCACACCGATGGGCACAGCTGAAGTGGCACCGGATACATCGCCTCGGAGCGGTCCGTCCTGCTG GCACCGGCTTGTGCAGGTGTTCCAGTCTAAGCAGTTCCGCTCTGCCAAGCTGGAGCGGCTGTACCAGCGG TACTTCTTCCAGATGAACCAGAGCAGCCTCACGCTGCTCATGGCGGTGCTGGTGCTGCTCATGGCTGTAC TGTTGACTTTCCACGCTGCGCCTGCCCAGCCTCAGCCTGCTTACGTGGCCCTGCTGACCTGTGCCTCTGT CCTTTTTGTGGTACTCATGGTGGTGTGTAACCGACACAGCTTCCGCCAGGACTCCATGTGGGTGGTGAGC TATGTGGTCCTGGGCATCCTAGCAGCCGTGCAAGTCGGGGGTGCCCTGGCAGCCAATCCACACAGCCCCT CGGCGGGCCTTTGGTGCCCCGTGTTCTTCGTCTACATCACCTACACTCTTCTTCCCATTCGCATGCGAGC CGCAGTACTCAGCGGCCTGGGCCTCTCTACTCTGCATTTGATTTTGGCCTGGCAGCTCAACAGCAGCGAC CCCTTCCTTTGGAAGCAGCTCGGTGCTAACGTGGTGCTCTTCCTCTGCACCAATGCCATCGGTGTCTGCA CACACTACCCTGCTGAAGTGTCTCAGCGCCAAGCCTTTCAGGAGACCCGAGGTTACATCCAGGCGCGGCT GCACCTGCAGCATGAGAACCGTCAGCAGGAACGGCTGCTGCTATCGGTGTTGCCCCAGCACGTTGCCATG GAGATGAAAGAAGACATCAACACAAAAAAAGAGGACATGATGTTCCATAAGATCTACATCCAGAAGCATG ATAATGTCAGCATCCTGTTTGCGGACATTGAGGGCTTCACCAGCCTGGCCTCCCAGTGCACTGCACAGGA ACTGGTCATGACCTTGAATGAGCTCTTTGCCCGGTTTGACAAGCTGGCTGCGGTGAGGGAGAATCACTGT CTGAGGATCAAGATCTTAGGAGACTGTTACTACTGCGTGTCAGGGCTGCCCGAGGCCCGGGCAGATCACG CCCACTGCTGTGTGGAGATGGGGGTAGACATGATCGAAGCCATCTCGCTGGTGCGTGAGGTAACAGGTGT GAACGTGAACATGCGTGTGGGCATCCACAGCGGACGTGTGCATTGCGGCGTCCTTGGCCTACGGAAATGG CAGTTTGATGTCTGGTCAAACGATGTGACCCTGGCTAACCACATGGAGGCCGGGGGCCGGGCCGGCCGCA TCCACATCACTCGGGCTACACTGCAGTACTTGAACGGGGACTATGAGGTGGAGCCAGGCCGTGGTGGTGA ACGCAATGCGTACCTCAAGGAGCAGTGCATTGAGACCTTCCTCATACTTGGCGCCAGCCAAAAACGGAAA GAGGAGAAAGCCATGCTGGCCAAGCTTCAGCGGACACGGGCCAACTCCATGGAAGGACTGATGCCCCGCT GGGTTCCTGACCGTGCCTTCTCCCGGACCAAGGACTCTAAGGCATTCCGCCAGATGGGCATTGATGATTC TAGCAAAGACAACCGGGGTGCCCAAGATGCTCTGAACCCTGAAGATGAGGTGGATGAGTTCCTGGGCCGA GCCATCGATGCCCGAAGCATCGACCAACTGCGTAAGGACCATGTGCGCCGGTTCCTGCTCACCTTCCAGA GAGAGGATCTTGAGAAGAAGTATTCACGGAAAGTAGATCCTCGCTTCGGAGCCTACGTCGCCTGTGCCCT CCTGGTTTTTTGCTTCATCTGTTTTATCCAGCTCCTTGTGTTCCCATACTCCACCCTGATACTCGGGATT TATGCCGCTATCTTCCTGCTGTTGCTGGTCACTGTGCTGATCTGTGCCGTGTGCTCCTGCGGTTCTTTCT TCCCCAAGGCCCTGCAACGCCTGTCCCGCAATATTGTCCGCTCACGGGTGCACAGCACCGCGGTTGGAAT CTTCTCGGTTCTGCTTGTGTTCATCTCTGCCATCGCCAACATGTTTACCTGTAATCACACCCCAATAAGG ACCTGCGCGGCCCGGATGCTGAACTTAACACCAGCGGATGTCACCGCCTGCCACCTACAACAGCTCAATT ACTCTCTGGGACTGGATGCTCCCCTGTGTGAGGGCACCGCACCCACCTGCAGCTTCCCTGAGTACTTCGT CGGGAACGTGCTGCTGAGTCTTCTAGCCAGCTCTGTCTTCCTACACATCAGCAGCATCGGCAAGCTGGCC ATGACCTTCATCTTGGGGTTCACCTACTTGGTGCTGCTTTTGCTGGGTCCCCCGGCCGCCATCTTTGACA ACTATGATCTACTGCTTGGCGTCCATGGCTTGGCTTCCTCCAATGAGACCTTTGATGGGCTGGACTGCCC AGCTGTGGGGAGGGTAGCGCTCAAATATATGACCCCCGTGATTCTGCTGGTGTTTGCCCTGGCACTGTAT CTGCATGCACAACAGGTGGAATCGACTGCCCGCCTGGACTTCCTGTGGAAGTTACAGGCAACAGGGGAGA AGGAGGAGATGGAGGAGCTACAGGCATACAACCGGAGGTTGCTGCATAACATTCTTCCCAAGGACGTGGC CGCCCACTTCCTGGCCCGGGAACGCCGCAACGATGAGCTGTACTACCAGTCGTGTGAATGTGTGGCTGTC ATGTTTGCCTCCATCGCCAATTTCTCGGAGTTCTACGTGGAGCTCGAGGCAAACAACGAGGGCGTGGAGT GCCTGCGGCTGCTCAATGAGATCATCGCAGACTTTGACGAGATCATCAGTGAGGAGAGATTCCGGCAGTT GGAGAAGATCAAGACCATCGGTAGCACCTACATGGCCGCCTCTGGGCTAAATGCCAGCACCTATGACCAG GTCGGCCGCTCACACATCACGGCGCTGGCTGACTATGCCATGCGGCTCATGGAGCAGATGAAACACATCA ATGAACACTCTTTCAACAATTTCCAGATGAAGATCGGGTTGAACATGGGTCCGGTTGTAGCAGGCGTCAT TGGGGCCCGAAAGCCACAGTATGACATCTGGGGAAATACCGTGAATGTTTCCAGTCGTATGGACAGCACT GGAGTTCCTGACCGAATACAGGTGACTACGGACCTATACCAGGTTCTAGCTGCCAAGGGCTACCAGCTGG AGTGTCGAGGGGTGGTCAAGGTGAAGGGAAAGGGGGAGATGACCACCTACTTCCTCAACGGGGGCCCCAG CAGT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG226872 representing NM_007405
Red=Cloning site Green=Tags(s) MSWFSGLLVPKVDERKTAWGERNGQKRPRHANRASGFCAPRYMSCLKNAEPPSPTPAAHTRCPWQDEAFI RRAGPGRGVELGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRLVQVFQSKQFRSAKLERLYQR YFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPAQPQPAYVALLTCASVLFVVLMVVCNRHSFRQDSMWVVS YVVLGILAAVQVGGALAANPHSPSAGLWCPVFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWQLNSSD PFLWKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAM EMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAVRENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKW QFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQCIETFLILGASQKRK EEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKDNRGAQDALNPEDEVDEFLGR AIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLVFPYSTLILGI YAAIFLLLLVTVLICAVCSCGSFFPKALQRLSRNIVRSRVHSTAVGIFSVLLVFISAIANMFTCNHTPIR TCAARMLNLTPADVTACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNVLLSLLASSVFLHISSIGKLA MTFILGFTYLVLLLLGPPAAIFDNYDLLLGVHGLASSNETFDGLDCPAVGRVALKYMTPVILLVFALALY LHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAV MFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQ VGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDST GVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007405 |
| ORF Size | 3504 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007405.3 |
| RefSeq Size | 6038 bp |
| RefSeq ORF | 3507 bp |
| Locus ID | 11512 |
| UniProt ID | Q01341 |
| Gene Summary | Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:18071070, PubMed:24363043). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:18071070). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption (PubMed:20466003, PubMed:20864687). Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion (PubMed:24854272). Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (PubMed:23753526). Signaling mediates cAMP-dependent activation of protein kinase PKA and promotes increased phosphorylation of various proteins, including AKT (PubMed:18071070, PubMed:23753526). Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility (PubMed:18071070). May contribute to normal heart function (PubMed:18071070, PubMed:20359598). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (By similarity). Contributes to bone cell responses to mechanical stimuli (PubMed:20371630, PubMed:24277577).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223787 | Adcy6 (untagged) - Mouse adenylate cyclase 6 (Adcy6), (10ug) |
CNY 15,010.00 |
|
| MR226872 | Adcy6 (Myc-DDK-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CNY 8,136.00 |
|
| MR226872L3 | Lenti ORF clone of Adcy6 (Myc-DDK-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CNY 11,500.00 |
|
| MR226872L4 | Lenti ORF clone of Adcy6 (mGFP-tagged) - Mouse adenylate cyclase 6 (Adcy6) |
CNY 11,500.00 |
