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Pdzk1 (NM_001146001) Mouse Tagged ORF Clone
CAT＃: MR223822
- TrueORF®
Pdzk1 (Myc-DDK-tagged) - Mouse PDZ domain containing 1 (Pdzk1), transcript variant 2
ORF Plasmid: tGFP
"NM_001146001" in other vectors (3)
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CNY 4,470.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 1700023D20Rik; 2610507N21Rik; 4921513F16Rik; AI267131; AI314638; AL022680; D3Ertd537e |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR223822 representing NM_001146001
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCTCCACCTTCAACCCCAGAGAGTGTAAATTGTCCAAACAAGAGGGGCAGAACTATGGCTTCTTTC TCCGAATTGAGAAGGACACTGATGGTCACCTGATCCGGGTGATTGAGGAGGGGAGCCCAGCAGAGAAGGC GGGGCTCCTGGACGGTGACAGGGTGCTCAGGATCAATGGTGTCTTTGTCGACAAGGAGGAGCATGCGCAG GTGGTGGAGCTGGTCAGAAAGAGTGGGAATTCAGTGACTCTGCTGGTCCTGGATGGAGACTCCTATGAGA AGGCTGTGAAAAATCAGGTGGATTTGAAAGAGCTGGATCAAAGCCAGAGGGAGGCCGCTCTGAATGATAA GAAACCGGGCCCTGGGATGAACGGAGCGGTGGAGCCGTGTGCCCAGCCACGGCTCTGCTACCTGGTGAAG GAGGGCAACAGCTTTGGCTTCTCTCTGAAAACTATCCAAGGTAAAAAGGGTGTGTACTTGACTAATATAA TGCCTCAGGGCGTGGCCATGAAAGCTGGTGTTCTGGCTGATGATCACTTGATTGAAGTGAATGGAGAAAA TGTAGAGAACGCCAGCCATGAGGAAGTGGTTGAAAAGGTGACAAAGTCAGGAAGCCGTATCATGTTCCTC CTTGTGGACAAAGAAACTGCCAGGTGCCATAGTGAACAGAAGACACAATTCAAGAGGGAGACAGCCAGTT TGAAACTGCTGCCCCACCAGCCCCGGGTGGTAGTGATCAAGAAGGGCAGCAATGGCTATGGCTTCTATCT GAGGGCGGGGCCTGAACAGAAAGGTCAAATCATTAAGGACATAGAACCCGGGAGCCCAGCAGAGGCAGCT GGCTTGAAGAACAATGACTTGGTAGTTGCTGTCAATGGCAAGTCTGTGGAAGCTCTTGATCATGACGGTG TGGTGGAAATGATTAGAAAAGGTGGAGACCAGACTACTCTGTTGGTGCTGGACAAAGAGGCAGAGAGCAT CTATAGCCTGGCTCGGTTCTCTCCACTTCTTTACTGCCAAAGTCAAGAACTGCCTAATGGTTCTGTCAAG GAAGGCCCAGCTCCGATCCCTGCTCCTCTGGAGGCCACAGGCTCAGAGCCCACAGAGGACGCGGAGGGTC ACAAGCCCAAGCTCTGCAGGCTGCTTAAAGAGGACGATAGCTACGGCTTTCACCTGAATGCCATTCGGGG TCAGCCTGGCTCCTTTGTCAAAGAGGTACAGCAGGGTGGCCCTGCTGACAAGGCTGGGCTGGAGAATGAG GACGTCATCATCGAAGTGAACGGGGAGAACGTGCAAGAGGAACCCTACGACAGAGTGGTGGAGAGAATCA AGAGCAGCGGGAAGCACGTCACTCTGTTGGTCTGTGGAAAGATGGCCTACAGCTACTTCCAAGCTAAGAA AATCCCCATCGTTTCCTCCATGGCCGAGCCCCTGGTGGCTGGCCCTGATGAAAAAGGAGAGACGTCTGCG GAGTCCGAGCATGACGCCCACCCAGCAAAAGACCGAACTCTCAGCACAGCCTCGCACTCTTCGTCTAACT CTGAAGACACGGAGATG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR223822 representing NM_001146001
Red=Cloning site Green=Tags(s) MASTFNPRECKLSKQEGQNYGFFLRIEKDTDGHLIRVIEEGSPAEKAGLLDGDRVLRINGVFVDKEEHAQ VVELVRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQSQREAALNDKKPGPGMNGAVEPCAQPRLCYLVK EGNSFGFSLKTIQGKKGVYLTNIMPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFL LVDKETARCHSEQKTQFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAA GLKNNDLVVAVNGKSVEALDHDGVVEMIRKGGDQTTLLVLDKEAESIYSLARFSPLLYCQSQELPNGSVK EGPAPIPAPLEATGSEPTEDAEGHKPKLCRLLKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENE DVIIEVNGENVQEEPYDRVVERIKSSGKHVTLLVCGKMAYSYFQAKKIPIVSSMAEPLVAGPDEKGETSA ESEHDAHPAKDRTLSTASHSSSNSEDTEM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001146001 |
| ORF Size | 1557 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001146001.2 |
| RefSeq Size | 2389 bp |
| RefSeq ORF | 1560 bp |
| Locus ID | 59020 |
| UniProt ID | Q9JIL4 |
| MW | 56.9 kDa |
| Gene Summary | A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity (By similarity). Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223822 | Pdzk1 (tGFP-tagged) - Mouse PDZ domain containing 1 (Pdzk1) transcript variant 2, (10ug) |
CNY 4,940.00 |
|
| MR223822L3 | Lenti ORF clone of Pdzk1 (Myc-DDK-tagged) - Mouse PDZ domain containing 1 (Pdzk1), transcript variant 2 |
CNY 6,370.00 |
|
| MR223822L4 | Lenti ORF clone of Pdzk1 (mGFP-tagged) - Mouse PDZ domain containing 1 (Pdzk1), transcript variant 2 |
CNY 6,370.00 |
