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Bmpr2 (NM_007561) Mouse Tagged ORF Clone
CAT＃: MR226598
- TrueORF®
Bmpr2 (Myc-DDK-tagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2)
ORF Plasmid: tGFP
"NM_007561" in other vectors (4)
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CNY 10,840.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 2610024H22Rik; AL117858; AW546137; BB189135; BM; BMP; BMP-; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR226598 representing NM_007561
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTTCCTCGCTGCATCGGCCCTTTCGGGTGCCCTGGCTGCTATGGGCCGTCCTGCTGGTCAGCACTA CGGCTGCTTCTCAGAATCAAGAACGGCTGTGTGCATTTAAAGATCCATATCAACAAGATCTTGGGATAGG TGAGAGTCGAATCTCTCATGAAAATGGGACAATATTATGTTCCAAAGGGAGCACGTGTTATGGTCTGTGG GAGAAATCAAAAGGGGACATCAATCTTGTGAAACAAGGATGTTGGTCTCACATCGGTGATCCCCAAGAGT GCCACTATGAAGAGTGTGTAGTAACTACCACCCCACCCTCAATTCAGAATGGAACGTACCGCTTTTGCTG CTGTAGTACAGATTTATGTAATGTCAACTTTACTGAGAACTTTCCACCCCCTGACACAACACCACTCAGT CCACCTCATTCATTTAATCGAGATGAAACGATAATCATTGCTTTGGCATCAGTTTCTGTGTTAGCTGTTT TGATAGTCGCCTTATGTTTTGGATACAGAATGTTGACAGGAGACCGGAAACAGGGTCTTCACAGCATGAA CATGATGGAGGCGGCAGCAGCAGAGCCCTCCCTTGACCTGGATAACCTGAAGCTGCTGGAGCTGATTGGA CGGGGTCGATACGGAGCAGTATATAAAGGTTCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTATTTTCTT TTGCAAACCGTCAGAATTTTATAAATGAAAAAAACATTTACAGAGTGCCTTTGATGGAACATGACAACAT TGCTCGCTTCATAGTTGGAGACGAGAGGCTCACTGCAGACGGCCGCATGGAGTATTTGCTTGTGATGGAG TATTATCCCAATGGATCTCTGTGCAAATATCTGAGTCTCCACACAAGTGATTGGGTAAGCTCTTGCCGTC TGGCTCATTCTGTGACTAGAGGACTGGCTTATCTTCACACAGAATTACCACGAGGAGATCATTATAAACC CGCAATCTCCCACCGAGATTTAAACAGCAGGAATGTCCTGGTAAAGAATGACGGCGCGTGTGTTATCAGT GACTTTGGTTTATCCATGAGGCTAACTGGAAATCGGCTGGTGCGCCCAGGGGAAGAAGATAATGCGGCTA TAAGTGAGGTTGGCACAATTCGCTATATGGCACCAGAAGTGCTAGAAGGAGCTGTGAACCTGAGGGACTG TGAGTCAGCTCTGAAGCAAGTGGACATGTATGCGCTTGGACTCATCTACTGGGAGGTGTTTATGAGGTGT ACAGACCTCTTCCCAGGTGAATCTGTACCAGATTACCAGATGGCTTTTCAGACAGAAGTTGGAAACCATC CCACATTTGAGGATATGCAGGTTCTTGTGTCCAGAGAGAAGCAGAGACCCAAGTTCCCAGAAGCCTGGAA AGAAAATAGCCTGGCAGTGAGGTCACTCAAGGAAACAATTGAAGACTGCTGGGACCAGGATGCAGAGGCT CGGCTCACTGCACAGTGTGCTGAGGAGAGGATGGCTGAACTCATGATGATATGGGAGAGAAACAAGTCTG TGAGCCCAACGGTCAACCCAATGTCAACTGCTATGCAGAATGAACGCAACCTGTCACATAATAGGCGTGT GCCAAAAATCGGGCCTTACCCAGATTATTCCTCTTCCTCATATATTGAAGACTCTATCCATCATACTGAC AGCATTGTGAAGAATATTTCCTCTGAGCATTCGATGTCCAGCACACCATTGACAATAGGAGAAAAGAATC GAAATTCAATTAATTATGAACGACAGCAAGCACAAGCTCGAATCCCTAGCCCAGAAACAAGCGTCACAAG CCTGTCCACAAACACAACCACCACAAACACCACCGGCCTCACTCCAAGTACTGGCATGACCACTATATCT GAGATGCCATACCCAGATGAGACACATTTGCACGCCACAAATGTTGCACAGTCAATCGGGCCAACCCCTG TCTGCTTACAGCTGACAGAAGAAGACTTGGAGACTAATAAGCTAGATCCAAAAGAAGTTGATAAGAACCT CAAGGAAAGCTCTGATGAGAATCTCATGGAGCATTCTCTGAAGCAGTTCAGTGGGCCAGACCCATTGAGC AGTACCAGTTCTAGCTTGCTTTATCCACTCATAAAGCTCGCAGTGGAAGTGACTGGACAACAGGACTTCA CACAGGCTGCAAATGGGCAAGCATGTTTAATTCCTGATGTTCCACCTGCTCAGATCTATCCTCTCCCTAA GCAACAGAACCTTCCTAAGAGACCTACTAGTTTGCCTTTGAACACCAAAAATTCAACAAAAGAACCCCGG CTAAAATTTGGCAACAAGCACAAATCAAACTTGAAACAAGTAGAAACTGGAGTTGCCAAGATGAATACAA TCAATGCAGCAGAGCCTCATGTGGTGACAGTAACTATGAATGGTGTGGCAGGTAGAAGCCACAATGTTAA TTCCCATGCTGCCACAACCCAGTATGCCAATGGCGCAGTGCCAGCTGGCCAGGCAGCCAACATAGTGGCA CATAGGTCCCAAGAAATGCTGCAGAATCAATTTATTGGTGAGGATACCAGGCTGAATATCAATTCCAGTC CTGATGAGCATGAACCTTTACTGAGACGAGAGCAACAGGCTGGCCATGATGAAGGGGTTCTGGATCGTTT GGTAGATAGGAGGGAACGGCCATTAGAAGGTGGCCGAACAAATTCCAATAACAACAACAGCAATCCATGT TCAGAACAAGATATCCTTACACAAGGTGTTACAAGCACAGCTGCAGATCCTGGGCCATCAAAGCCCAGAA GAGCACAGAGGCCCAATTCTCTGGATCTTTCAGCCACAAATATCCTGGATGGCAGCAGTATACAGATAGG TGAGTCAACACAAGATGGCAAATCAGGATCAGGTGAAAAGATCAAGAGACGTGTGAAAACTCCATACTCT CTTAAGCGGTGGCGCCCGTCCACCTGGGTCATCTCCACCGAGCCGCTGGACTGTGAGGTCAACAACAATG GCAGTGACAGGGCAGTCCATTCTAAATCTAGCACTGCTGTGTACCTTGCAGAGGGAGGCACTGCCACGAC CACAGTGTCTAAAGATATAGGAATGAATTGTCTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR226598 representing NM_007561
Red=Cloning site Green=Tags(s) MTSSLHRPFRVPWLLWAVLLVSTTAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLW EKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLS PPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAAAEPSLDLDNLKLLELIG RGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERLTADGRMEYLLVME YYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGACVIS DFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEVFMRC TDLFPGESVPDYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEA RLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTD SIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTIS EMPYPDETHLHATNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLS STSSSLLYPLIKLAVEVTGQQDFTQAANGQACLIPDVPPAQIYPLPKQQNLPKRPTSLPLNTKNSTKEPR LKFGNKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRSHNVNSHAATTQYANGAVPAGQAANIVA HRSQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPC SEQDILTQGVTSTAADPGPSKPRRAQRPNSLDLSATNILDGSSIQIGESTQDGKSGSGEKIKRRVKTPYS LKRWRPSTWVISTEPLDCEVNNNGSDRAVHSKSSTAVYLAEGGTATTTVSKDIGMNCL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007561 |
| ORF Size | 3114 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007561.4, NP_031587.1 |
| RefSeq Size | 3507 bp |
| RefSeq ORF | 3117 bp |
| Locus ID | 12168 |
| UniProt ID | O35607 |
| MW | 115.5 kDa |
| Gene Summary | This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses
,Mundy, C;Yang, E;Takano, H;Billings, PC;Pacifici, M;,
J. Biol. Chem.
,PubMed ID 29622677
[BMPR2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223313 | Bmpr2 (untagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2), (10ug) |
CNY 10,848.00 |
|
| MG226598 | Bmpr2 (tGFP-tagged) - Mouse bone morphogenic protein receptor type II (serine/threonine kinase) (Bmpr2), (10ug) |
CNY 12,440.00 |
|
| MR226598L3 | Lenti ORF clone of Bmpr2 (Myc-DDK-tagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2) |
CNY 12,260.00 |
|
| MR226598L4 | Lenti ORF clone of Bmpr2 (mGFP-tagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2) |
CNY 12,260.00 |
