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GPR37L1 (NM_004767) Human Tagged ORF Clone
CAT＃: RG208132
- TrueORF®
GPR37L1 (tGFP-tagged) - Human G protein-coupled receptor 37 like 1 (GPR37L1)
ORF Plasmid: DDK
"NM_004767" in other vectors (4)
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CNY 7,088.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ET(B)R-LP-2; ETBR-LP-2; ETBRLP2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG208132 representing NM_004767
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGTGGCTGTGGCCCCTGGCTGTCTCTCTTGCTGTGATTTTGGCTGTGGGGCTAAGCAGGGTCTCTG GGGGTGCCCCCCTGCACCTGGGCAGGCACAGAGCCGAGACCCAGGAGCAGCAGAGCCGATCCAAGAGGGG CACCGAGGATGAGGAGGCCAAGGGCGTGCAGCAGTATGTGCCTGAGGAGTGGGCGGAGTACCCCCGGCCC ATTCACCCTGCTGGCCTGCAGCCAACCAAGCCCTTGGTGGCCACCAGCCCTAACCCCGGCAGGGATGGGG GCACCCCAGACAGTGGGCAGGAACTGAGGGGCAATCTGACAGGAGCACCAGGGCAGAGGCTACAGATCCA GAACCCCCTGTATCCGGTGACCGAGAGCTCCTACAGTGCCTATGCCATCATGCTTCTGGCGCTGGTGGTG TTTGCGGTGGGCATTGTGGGCAACCTGTCGGTCATGTGCATCGTGTGGCACAGCTACTACCTGAAGAGTG CCTGGAACTCCATCCTTGCCAGCCTGGCCCTCTGGGATTTTCTGGTCCTCTTTTTCTGCCTCCCTATTGT CATCTTCAACGAGATCACCAAGCAGAGGCTACTGGGTGACGTTTCTTGTCGTGCCGTGCCCTTCATGGAG GTCTCCTCTCTGGGAGTCACGACTTTCAGCCTCTGTGCCCTGGGCATTGACCGCTTCCACGTGGCCACCA GCACCCTGCCCAAGGTGAGGCCCATCGAGCGGTGCCAATCCATCCTGGCCAAGTTGGCTGTCATCTGGGT GGGCTCCATGACGCTGGCTGTGCCTGAGCTCCTGCTGTGGCAGCTGGCACAGGAGCCTGCCCCCACCATG GGCACCCTGGACTCATGCATCATGAAACCCTCAGCCAGCCTGCCCGAGTCCCTGTATTCACTGGTGATGA CCTACCAGAACGCCCGCATGTGGTGGTACTTTGGCTGCTACTTCTGCCTGCCCATCCTCTTCACAGTCAC CTGCCAGCTGGTGACATGGCGGGTGCGAGGCCCTCCAGGGAGGAAGTCAGAGTGCAGGGCCAGCAAGCAC GAGCAGTGTGAGAGCCAGCTCAACAGCACCGTGGTGGGCCTGACCGTGGTCTACGCCTTCTGCACCCTCC CAGAGAACGTCTGCAACATCGTGGTGGCCTACCTCTCCACCGAGCTGACCCGCCAGACCCTGGACCTCCT GGGCCTCATCAACCAGTTCTCCACCTTCTTCAAGGGCGCCATCACCCCAGTGCTGCTCCTTTGCATCTGC AGGCCGCTGGGCCAGGCCTTCCTGGACTGCTGCTGCTGCTGCTGCTGTGAGGAGTGCGGCGGGGCTTCGG AGGCCTCTGCTGCCAATGGGTCGGACAACAAGCTCAAGACCGAGGTGTCCTCTTCCATCTACTTCCACAA GCCCAGGGAGTCACCCCCACTCCTGCCCCTGGGCACACCTTGC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004767 |
| ORF Size | 1443 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004767.2, NP_004758.2 |
| RefSeq Size | 2516 bp |
| RefSeq ORF | 1446 bp |
| Locus ID | 9283 |
| UniProt ID | O60883 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Gene Summary | G-protein coupled receptor (PubMed:27072655). Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (PubMed:23690594). However, other studies have shown that prosaposin does not increase activity (PubMed:27072655, PubMed:28688853). It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha (PubMed:27072655). Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway (By similarity). Regulates baseline blood pressure in females and protects against cardiovascular stress in males (By similarity). Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells
,Hertz, E;Terenius, L;Vukojević, V;Svenningsson, P;,
Neuropharmacology
,PubMed ID 30423289
[GPR37L1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208132 | GPR37L1 (Myc-DDK-tagged)-Human G protein-coupled receptor 37 like 1 (GPR37L1) |
CNY 5,488.00 |
|
| RC208132L3 | Lenti-ORF clone of GPR37L1 (Myc-DDK-tagged)-Human G protein-coupled receptor 37 like 1 (GPR37L1) |
CNY 5,890.00 |
|
| RC208132L4 | Lenti-ORF clone of GPR37L1 (mGFP-tagged)-Human G protein-coupled receptor 37 like 1 (GPR37L1) |
CNY 5,890.00 |
|
| SC117166 | GPR37L1 (untagged)-Human G protein-coupled receptor 37 like 1 (GPR37L1) |
CNY 5,488.00 |
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