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Proprotein convertase PC4 (PCSK4) (NM_017573) Human Untagged Clone
CAT＃: SC318233
PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4)
CNY 14,540.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PC4; SPC5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318233 representing NM_017573.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCGGCCCGCCCCGATTGCGCTGTGGCTGCGCCTGGTCTTGGCCCTGGCCCTTGTCCGCCCCCGGGCT GTGGGGTGGGCCCCGGTCCGAGCCCCCATCTATGTCAGCAGCTGGGCCGTCCAGGTGTCCCAGGGTAAC CGGGAGGTCGAGCGCCTGGCACGCAAATTCGGCTTCGTCAACCTGGGGCCGATCTTCCCTGACGGGCAG TACTTTCACCTGCGGCACCGGGGCGTGGTCCAGCAGTCCCTGACCCCGCACTGGGGCCACCGCCTGCAC CTGAAGAAAAACCCCAAGGTGCAGTGGTTCCAGCAGCAGACGCTGCAGCGGCGGGTGAAACGCTCTGTC GTGGTGCCCACGGACCCCTGGTTCTCCAAGCAGTGGTACATGAACAGCGAGGCCCAACCAGACCTGAGC ATCCTGCAGGCCTGGAGTCAGGGGCTGTCAGGCCAGGGCATCGTGGTCTCTGTGCTGGACGATGGCATC GAGAAGGACCACCCGGACCTCTGGGCCAACTACGACCCCCTGGCCAGCTATGACTTCAATGACTACGAC CCGGACCCCCAGCCCCGCTACACCCCCAGCAAAGAGAACCGGCACGGGACCCGCTGTGCTGGGGAGGTG GCCGCGATGGCCAACAATGGCTTCTGTGGTGTGGGGGTCGCTTTCAACGCCCGAATCGGAGGCGTACGG ATGCTGGACGGTACCATCACCGATGTCATCGAGGCCCAGTCGCTGAGCCTGCAGCCGCAGCACATCCAC ATTTACAGCGCCAGCTGGGGTCCCGAGGACGACGGCCGCACGGTGGACGGCCCCGGCATCCTCACCCGC GAGGCCTTCCGGCGTGGTGTGACCAAGGGCCGCGGCGGGCTGGGCACGCTCTTCATCTGGGCCTCGGGC AACGGCGGCCTGCACTACGACAACTGCAACTGCGACGGCTACACCAACAGCATCCACACGCTTTCCGTG GGCAGCACCACCCAGCAGGGCCGCGTGCCCTGGTACAGCGAAGCCTGCGCCTCCACCCTCACCACCACC TACAGCAGCGGCGTGGCCACCGACCCCCAGATCGTCACCACGGACCTGCATCACGGGTGCACAGACCAG CACACGGGCACCTCGGCCTCAGCCCCACTGGCGGCCGGCATGATCGCCCTAGCGCTGGAGGCCAACCCG TTCCTGACGTGGAGAGACATGCAGCACCTGGTGGTCCGCGCGTCCAAGCCGGCGCACCTGCAGGCCGAG GACTGGAGGACCAACGGCGTGGGGCGCCAAGTGAGCCATCACTACGGATACGGGCTGCTGGACGCCGGG CTGCTGGTGGACACCGCCCGCACCTGGCTGCCCACCCAGCCGCAGAGGAAGTGCGCCGTCCGGGTCCAG AGCCGCCCCACCCCCATCCTGCCGCTGATCTACATCAGGGAAAACGTATCGGCCTGCGCCGGCCTCCAC AACTCCATCCGCTCGCTGGAGCACGTGCAGGCGCAGCTGACGCTGTCCTACAGCCGGCGCGGAGACCTG GAGATCTCGCTCACCAGCCCCATGGGCACGCGCTCCACACTCGTGGCCATACGACCCTTGGACGTCAGC ACTGAAGGCTACAACAACTGGGTCTTCATGTCCACCCACTTCTGGGATGAGAACCCACAGGGCGTGTGG ACCCTGGGCCTAGAGAACAAGGGCTACTATTTCAACACGGGGACGTTGTACCGCTACACGCTGCTGCTC TATGGGACGGCCGAGGACATGACAGCGCGGCCTACAGGCCCCCAGGTGACCAGCAGCGCGTGTGTGCAG CGGGACACAGAGGGGCTGTGCCAGGCGTGTGACGGCCCCGCCTACATCCTGGGACAGCTCTGCCTGGCC TACTGCCCCCCGCGGTTCTTCAACCACACAAGGCTGGTGACCGCTGGGCCTGGGCACACGGCGGCGCCC GCGCTGAGGGTCTGCTCCAGCTGCCATGCCTCCTGCTACACCTGCCGCGGCGGCTCCCCGAGGGACTGC ACCTCCTGTCCCCCATCCTCCACGCTGGACCAGCAGCAGGGCTCCTGCATGGGACCCACCACCCCCGAC AGCCGCCCCCGGCTTAGAGCTGCCGCCTGTCCCCACCACCGCTGCCCAGCCTCGGCCATGGTGCTGAGC CTCCTGGCCGTGACCCTCGGAGGCCCCGTCCTCTGCGGCATGTCCATGGACCTCCCACTATACGCCTGG CTCTCCCGTGCCAGGGCCACCCCCACCAAACCCCAGGTCTGGCTGCCAGCTGGAACCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_017573 |
| Insert Size | 2268 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017573.4 |
| RefSeq Size | 2716 bp |
| RefSeq ORF | 2268 bp |
| Locus ID | 54760 |
| UniProt ID | Q6UW60 |
| Protein Families | Druggable Genome, Protease |
| MW | 82.8 kDa |
| Gene Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. The protease is expressed only in the testis, placenta, and ovary. It plays a critical role in fertilization, fetoplacental growth, and embryonic development and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein and pro-insulin-like growth factor II. [provided by RefSeq, Jan 2014] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218596 | PCSK4 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4) |
CNY 5,528.00 |
|
| RC218596L1 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), Myc-DDK-tagged |
CNY 7,928.00 |
|
| RC218596L2 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), mGFP tagged |
CNY 9,790.00 |
|
| RC218596L3 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), Myc-DDK-tagged |
CNY 9,790.00 |
|
| RC218596L4 | Lenti ORF clone of Human proprotein convertase subtilisin/kexin type 4 (PCSK4), mGFP tagged |
CNY 9,790.00 |
|
| RG218596 | PCSK4 (tGFP-tagged) - Human proprotein convertase subtilisin/kexin type 4 (PCSK4) |
CNY 7,128.00 |
|
| SC311408 | PCSK4 (untagged)-Human proprotein convertase subtilisin/kexin type 4 (PCSK4) |
CNY 5,536.00 |
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