United States
Germany
Japan
United Kingdom
China
Itgb3bp (NM_026348) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201548L3V
- LentiORF®
-
Lenti ORF particles, Itgb3bp (Myc-DDK-tagged) - Mouse integrin beta 3 binding protein (beta3-endonexin) (Itgb3bp), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 7,410.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Itgb3bp (NM_026348) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4930471O16Rik; AU022583 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_026348 |
| ORF Size | 528 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201548).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_026348.3 |
| RefSeq Size | 2738 bp |
| RefSeq ORF | 531 bp |
| Locus ID | 67733 |
| Gene Summary | Transcription coregulator that can have both coactivator and corepressor functions. Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
其它Itgb3bp产品
Customer
Reviews
Loading...
