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Ebi3 (NM_015766) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202722L4V
- LentiORF®
-
Lenti ORF particles, Ebi3 (GFP-tagged) - Mouse Epstein-Barr virus induced gene 3 (Ebi3), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Ebi3 (NM_015766) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | EBI-3; IL-27 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_015766 |
| ORF Size | 687 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202722).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_015766.2, NP_056581.1 |
| RefSeq Size | 1187 bp |
| RefSeq ORF | 687 bp |
| Locus ID | 50498 |
| Gene Summary | Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.[UniProtKB/Swiss-Prot Function] |
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