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Scnm1 (NM_001163573) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR215391L4V
- LentiORF®
-
Lenti ORF particles, Scnm1 (GFP-tagged) - Mouse sodium channel modifier 1 (Scnm1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Scnm1 (NM_001163573) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 3110001I17Rik; Scnm1-ps |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001163573 |
| ORF Size | 492 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR215391).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001163573.1, NP_001157045.1 |
| RefSeq Size | 693 bp |
| RefSeq ORF | 495 bp |
| Locus ID | 69269 |
| Gene Summary | Mutations in the voltage-gated sodium channel gene Scn8a lead to neurological problems in mice. For one particular mutation, Scn8amedJ, mice live to adulthood but have tremors and muscle weakness, among other problems, in all strains except those derived from C57BL6 mice. In these strains, the product of the Scnm1 gene (229 aa) partially overcomes the effects of the Scn8amedJ mutation. However, in C57BL6-derived mice, a one nt change in the penultimate exon creates a premature stop codon, truncating the Scnm1 protein at 186 aa. This truncated protein lacks the ability to overcome the effects of the Scn8amedJ mutation, and these mice suffer paralysis and juvenile death. [provided by RefSeq, Jul 2009] |
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