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Chrne (NM_009603) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR224539L3V
- LentiORF®
-
Lenti ORF particles, Chrne (Myc-DDK-tagged) - Mouse cholinergic receptor, nicotinic, epsilon polypeptide (Chrne), 200ul, >10^7 TU/mL
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CNY 9,405.00
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Specifications
| Product Data | |
| Product Name | Chrne (NM_009603) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Ac; ACh; AChrepsilon; Acre; nAChRE |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009603 |
| ORF Size | 1479 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR224539).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009603.1, NP_033733.1 |
| RefSeq Size | 1599 bp |
| RefSeq ORF | 1482 bp |
| Locus ID | 11448 |
| Gene Summary | This gene encodes the epsilon subunit of the muscle-derived nicotinic acetylcholine receptor, a pentameric neurotransmitter receptor and member of the ligand-gated ion channel superfamily. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. In mice, deficiency of this gene can lead to a decline in the number of nicotinic acetylcholine receptors at neuromuscular junctions and causes progressive muscle weakness, atrophy and premature death. Mutations in this gene serve as a pathophysiological model for human congenital myasthenia. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Nov 2012] |
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