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Sh3kbp1 (NM_001135728) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226321L3V
- LentiORF®
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Lenti ORF particles, Sh3kbp1 (Myc-DDK-tagged) - Mouse SH3-domain kinase binding protein 1 (Sh3kbp1), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
| Product Data | |
| Product Name | Sh3kbp1 (NM_001135728) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1200007H22Rik; 1700125L08Rik; 5830464D22Rik; AI447724; Cin85; IN85; Ruk; Seta |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001135728 |
| ORF Size | 1281 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226321).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001135728.1, NP_001129200.1 |
| RefSeq Size | 4167 bp |
| RefSeq ORF | 1284 bp |
| Locus ID | 58194 |
| Gene Summary | Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may be inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit. May be involved in regulation of cell adhesion; promotes the interaction between TTK2B and PDCD6IP. May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4. Is involved in modulation of tumor necrosis factor mediated apoptosis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration (By similarity).[UniProtKB/Swiss-Prot Function] |
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