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Cathepsin K (CTSK) (NM_000396) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204892L2V
- LentiORF®
-
Lenti ORF particles, CTSK (mGFP-tagged) - Human cathepsin K (CTSK), 200ul, >10^7 TU/mL
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CNY 9,120.00
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| Product Data | |
| Product Name | Cathepsin K (CTSK) (NM_000396) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD |
| Vector | pLenti-C-mGFP |
| ACCN | NM_000396 |
| ORF Size | 987 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204892).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000396.2 |
| RefSeq Size | 1825 bp |
| RefSeq ORF | 990 bp |
| Locus ID | 1513 |
| Domains | Pept_C1 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Lysosome |
| MW | 37 kDa |
| Gene Summary | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] |
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