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BMP5 (NM_021073) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC206456L1V
- LentiORF®
-
Lenti ORF particles, BMP5 (Myc-DDK tagged) - Human bone morphogenetic protein 5 (BMP5), 200ul, >10^7 TU/mL
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CNY 8,930.00
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| Product Data | |
| Product Name | BMP5 (NM_021073) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_021073 |
| ORF Size | 1362 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC206456).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021073.2 |
| RefSeq Size | 2207 bp |
| RefSeq ORF | 1365 bp |
| Locus ID | 653 |
| Domains | TGFb_propeptide, TGF-beta |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway |
| Protein Pathways | Hedgehog signaling pathway, TGF-beta signaling pathway |
| MW | 51.7 kDa |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] |
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