HIF1 beta (ARNT) (NM_178426) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217284L4V

  • LentiORF®

Lenti ORF particles, ARNT (mGFP-tagged) - Human aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,120.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name HIF1 beta (ARNT) (NM_178426) Human Tagged ORF Clone Lentiviral Particle
Synonyms aryl hydrocarbon receptor nuclear translocator; bHLHe2; dioxin receptor, nuclear translocator; HIF-1beta; HIF1B; HIF1BETA; hypoxia-inducible factor 1, beta subunit; OTTHUMP00000032943; TANGO
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_178426
ORF Size 984 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC217284).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_178426.1, NP_848513.1
RefSeq Size 3563 bp
RefSeq ORF 986 bp
Locus ID 405
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma
MW 35.8 kDa
Gene Summary This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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