DRP1 (DNM1L) (NM_012062) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221708L1V
- LentiORF®
Lenti ORF particles, DNM1L (Myc-DDK tagged) - Human dynamin 1-like (DNM1L), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 13,870.00
Cited in 3 publications. |
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CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | DRP1 (DNM1L) (NM_012062) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_012062 |
ORF Size | 2208 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221708).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012062.2 |
RefSeq Size | 3293 bp |
RefSeq ORF | 2211 bp |
Locus ID | 10059 |
Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
MW | 81.7 kDa |
Gene Summary | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
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Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy
,null,
The FASEB Journal
,PubMed ID 31291545
[DNM1L]
|
Mitochondrial protein 18 is a positive apoptotic regulator in cardiomyocytes under oxidative stress.
,null,
Clinical science (London, England : 1979)
,PubMed ID 31015359
[DNM1L]
|
Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons
,null,
Experimental neurology
,PubMed ID 19445933
[DNM1L]
|
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