United States
Germany
Japan
United Kingdom
China
Estrogen Receptor 1 (ESR1) (NM_001122742) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC226005L1V
- LentiORF®
-
Lenti ORF particles, ESR1 (Myc-DDK-tagged)-Human estrogen receptor 1 (ESR1), transcript variant 4, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | Estrogen Receptor 1 (ESR1) (NM_001122742) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ER; Era; ESR; ESRA; ESTRR; NR3A1 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_001122742 |
| ORF Size | 1785 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC226005).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001122742.1, NP_001116214.1 |
| RefSeq Size | 6466 bp |
| RefSeq ORF | 1788 bp |
| Locus ID | 2099 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| MW | 66.2 kDa |
| Gene Summary | This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020] |
Documents
| Product Manuals |
| FAQs |
| SDS |
