FZD3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 150-200of Human Frizzled-3.
Specificity	This antibody detects endogenous levels of Frizzled-3 protein. (region surrounding Leu180)
Formulation	Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). Preservative: 0.05% Sodium Azide
Concentration	1.0 mg/ml
Purification	Affinity Chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 76 kDa
Gene Name	frizzled class receptor 3
Database Link	Entrez Gene 7976 Human UniProt ID Q9NPG1
Background	FZD3 (Frizzled 3) belongs to the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD3 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Synonyms	Fz-3, hFz3
Reference Data

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