Nr5a2 (NM_030676) Mouse Tagged Lenti ORF Clone
CAT#: MR225371L3
- LentiORF®
Lenti ORF clone of Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1
"NM_030676" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 6,568.00
CNY 6,840.00
CNY 600.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | AU020803; D1Ertd308e; Ftf; LRH-1; UF2-H3B |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225371).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_030676 |
ORF Size | 1680 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_030676.3, NP_109601.1 |
RefSeq Size | 3720 bp |
RefSeq ORF | 1683 bp |
Locus ID | 26424 |
UniProt ID | P45448 |
Gene Summary | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity). Activates the transcription of CYP2C38 (PubMed:30555544).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC218968 | Nr5a2 (untagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1, (10ug) |
CNY 4,176.00 |
|
MG225371 | Nr5a2 (tGFP-tagged) - Mouse nuclear receptor subfamily 5 group A member 2 (Nr5a2) transcript variant 1, (10ug) |
CNY 5,420.00 |
|
MR225371 | Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1 |
CNY 4,168.00 |
|
MR225371L4 | Lenti ORF clone of Nr5a2 (mGFP-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1 |
CNY 6,840.00 |