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BIGM103 (SLC39A8) (NM_022154) Human Tagged ORF Clone
CAT＃: RG204200
- TrueORF®
SLC39A8 (tGFP-tagged) - Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1
ORF Plasmid: DDK
"NM_022154" in other vectors (7)
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CNY 4,370.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG204200 representing NM_022154
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCCCGGGTCGCGCGGTGGCCGGGCTCCTGTTGCTGGCGGCCGCCGGCCTCGGAGGAGTGGCGGAGG GGCCAGGGCTAGCCTTCAGCGAGGATGTGCTGAGCGTGTTCGGCGCGAATCTGAGCCTGTCGGCGGCGCA GCTCCAGCACTTGCTGGAGCAGATGGGAGCCGCCTCCCGCGTGGGCGTCCCGGAGCCTGGCCAGCTGCAC TTCAACCAGTGTTTAACTGCTGAAGAGATCTTTTCCCTTCATGGCTTTTCAAATGCTACCCAAATAACCA GCTCCAAATTCTCTGTCATCTGTCCAGCAGTCTTACAGCAATTGAACTTTCACCCATGTGAGGATCGGCC CAAGCACAAAACAAGACCAAGTCATTCAGAAGTTTGGGGATATGGATTCCTGTCAGTGACGATTATTAAT CTGGCATCTCTCCTCGGATTGATTTTGACTCCACTGATAAAGAAATCTTATTTCCCAAAGATTTTGACCT TTTTTGTGGGGCTGGCTATTGGGACTCTTTTTTCAAATGCAATTTTCCAACTTATTCCAGAGGCATTTGG ATTTGATCCCAAAGTCGACAGTTATGTTGAGAAGGCAGTTGCTGTGTTTGGTGGATTTTACCTACTTTTC TTTTTTGAAAGAATGCTAAAGATGTTATTAAAGACATATGGTCAGAATGGTCATACCCACTTTGGAAATG ATAACTTTGGTCCTCAAGAAAAAACTCATCAACCTAAAGCATTACCTGCCATCAATGGTGTGACATGCTA TGCAAATCCTGCTGTCACAGAAGCTAATGGACATATCCATTTTGATAATGTCAGTGTGGTATCTCTACAG GATGGAAAAAAAGAGCCAAGTTCATGTACCTGTTTGAAGGGGCCCAAACTGTCAGAAATAGGGACGATTG CCTGGATGATAACGCTCTGCGATGCCCTCCACAATTTCATCGATGGCCTGGCGATTGGGGCTTCCTGCAC CTTGTCTCTCCTTCAGGGACTCAGTACTTCCATAGCAATCCTATGTGAGGAGTTTCCCCACGAGTTAGGA GACTTTGTGATCCTACTCAATGCAGGGATGAGCACTCGACAAGCCTTGCTATTCAACTTCCTTTCTGCAT GTTCCTGCTATGTTGGGCTAGCTTTTGGCATTTTGGTGGGCAACAATTTCGCTCCAAATATTATATTTGC ACTTGCTGGAGGCATGTTCCTCTATATTTCTCTGGCAGATATGTTTCCAGAGATGAATGATATGCTGAGA GAAAAGGTAACTGGAAGAAAAACCGATTTCACCTTCTTCATGATTCAGAATGCTGGAATGTTAACTGGAT TCACAGCCATTCTACTCATTACCTTGTATGCAGGAGAAATCGAATTGGAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG204200 representing NM_022154
Red=Cloning site Green=Tags(s) MAPGRAVAGLLLLAAAGLGGVAEGPGLAFSEDVLSVFGANLSLSAAQLQHLLEQMGAASRVGVPEPGQLH FNQCLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPCEDRPKHKTRPSHSEVWGYGFLSVTIIN LASLLGLILTPLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVEKAVAVFGGFYLLF FFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQ DGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELG DFVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLR EKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEIELE TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_022154 |
| ORF Size | 1380 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022154.5, NP_071437.3 |
| RefSeq Size | 3309 bp |
| RefSeq ORF | 1383 bp |
| Locus ID | 64116 |
| UniProt ID | Q9C0K1 |
| Domains | Zip |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance
,null,
Frontiers in Physiology
,PubMed ID 35784893
[SLC39A8]
|
|
Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library
,null,
Chemmedchem
,PubMed ID 34309203
[SLC39A8]
|
|
A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity
,null,
Human Molecular Genetics
,PubMed ID 27466201
[SLC39A8]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204200 | SLC39A8 (Myc-DDK-tagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 3,656.00 |
|
| RC204200L1 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204200L2 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC204200L3 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204200L4 | Lenti ORF clone of Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| SC112817 | SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 2,950.00 |
|
| SC320928 | SLC39A8 (untagged)-Human solute carrier family 39 (zinc transporter), member 8 (SLC39A8), transcript variant 1 |
CNY 2,950.00 |
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