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DMTF1 (NM_021145) Human Untagged Clone
CAT＃: SC107975
DMTF1 (untagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DMP1; DMTF; hDMP1; MRUL |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC107975 sequence for NM_021145 edited (data generated by NextGen Sequencing)
ATGAGCACAGTGGAAGAGGATTCTGACACAGTAACAGTAGAAACTGTGAACTCTGTGACTTTGACTCAGG ACACAGAAGGGAATCTCATTCTTCACTGCCCTCAGAATGAAGCGGATGAAATAGACTCAGAAGATAGTAT TGAACCTCCACATAAAAGGCTTTGTTTGTCCTCTGAGGATGATCAGAGTATTGATGATTCTACTCCTTGC ATATCAGTTGTTGCACTTCCACTTTCAGAAAATGATCAGAGCTTTGAAGTGACCATGACTGCGACCACAG AAGTAGCAGATGATGAGGTTACTGAGGGGACTGTGACACAGATACAGATTTTGCAGAATGAGCAACTAGA TGAAATATCTCCCTTGGGTAACGAGGAAGTTTCAGCAGTTAGCCAAGCATGGTTTACAACTAAAGAAGAT AAGGATTCTCTGACTAATAAAGGACATAAATGGAAGCAGGGGATGTGGTCCAAGGAAGAAATTGATATTT TGATGAACAATATTGAACGCTATCTTAAGGCACGCGGAATAAAAGATGCTACAGAAATCATCTTTGAGAT GTCAAAAGACGAAAGAAAAGATTTCTACAGGACTATAGCATGGGGTCTGAACCGGCCTTTGTTTGCAGTT TATAGAAGAGTGCTTCGCATGTATGATGACAGAAACCATGTGGGAAAATATACACCTGAAGAAATTGAGA AGCTCAAGGAGCTCCGGATAAAGCATGGCAATGACTGGGCAACAATAGGGGCGGCGCTAGGAAGAAGTGC ATCTTCTGTCAAAGATCGGTGCCGACTGATGAAGGATACTTGCAACACAGGGAAGTGGACAGAAGAAGAA GAAAAGAGACTTGCAGAAGTGGTTCATGAGTTGACAAGCACTGAGCCAGGTGACATAGTCACACAGGGTG TGTCTTGGGCAGCTGTGGCTGAACGAGTCGGTACCCGCTCAGAAAAGCAATGTCGTTCTAAATGGCTCAA CTACCTGAATTGGAAACAGAGTGGGGGTACTGAATGGACCAAGGAAGATGAAATCAATCTCATCCTCAGG ATAGCAGAACTTGATGTAGCTGATGAAAATGACATTAACTGGGATCTGTTAGCTGAGGGATGGAGTAGTG TCCGTTCACCACAATGGCTACGAAGTAAATGGTGGACCATCAAAAGGCAAATTGCAAACCATAAGGATGT TTCGTTCCCTGTCTTAATAAAAGGTCTTAAACAGTTACATGAGAACCAAAAAAACAACCCAACGCTTTTG GAGAATAAATCAGGATCTGGAGTTCCAAACAGTAATACCAATTCCAGTGTGCAGCATGTTCAGATAAGAG TTGCCCGCTTGGAAGATAATACAGCCATCTCTTCTAGCCCCATGGCAGCATTGCAGATTCCAGTCCAGAT CACCCATGTTTCTTCAGCAGACTCTCCTGCTACCGTTGACTCAGAAACAATAACACTAAACAGTGGAACA CTACAGACATTTGAGATTCTTCCCTCTTTCCATCTACAGCCCACTGGCACTCCAGGCACCTACCTACTTC AAACAAGCTCAAGCCAAGGCCTTCCCCTAACTCTGACTGCTAGTCCCACAGTAACCCTGACAGCTGCTGC TCCTGCTTCTCCTGAACAGATTATTGTTCATGCTTTATCCCCAGAACATTTGTTGAACACAAGTGATAAT GTTACAGTGCAGTGTCACACACCAAGAGTCATCATTCAGACTGTTGCCACAGAGGACATCACTTCTTCCA TATCCCAAGCAGAACTGACAGTCGATAGTGATATTCAGTCATCTGATTTTCCTGAGCCTCCAGACGCCCT AGAAGCAGACACTTTCCCAGATGAAATTCATCACCCTAAGATGACTGTGGAGCCATCATTTAATGATGCT CATGTATCCAAATTCAGTGACCAAAATAGCACAGAACTGATGAATAGTGTTATGGTCAGAACAGAAGAAG AAATCTCTGACACCGACCTTAAACAAGAGGAATCACCCTCTGATTTAGCCAGTGCTTATGTTACTGAGGG TTTAGAGTCTCCCACTATAGAAGAACAAGTTGATCAAACAATTGATGATGAAACAATACTTATCGTTCCT TCACCACATGGCTTTATCCAGGCATCTGATGTTATAGATACTGAATCTGTCTTGCCTTTGACAACACTAA CAGATCCCATACTCCAACATCATCAGGAAGAATCAAATATCATTGGATCATCCTTGGGCAGTCCTGTTTC AGAAGATTCAAAGGATGTCGAAGATTTGGTAAACTGTCATTAG Clone variation with respect to NM_021145.3 273:g=>a >OriGene 5' read for NM_021145 unedited
TTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGCCACTCTCGCCCGT GGCTGCTTCCTCCATCCTGGTATTTTTTGGAGCTTCCATCCTGGTTCTTCCAAAGTGCCC GGACCCAAAACAGGAAAGTGTTGCGGAGATAGGAACATGGGAGAGAAACAATCTGGGTAA CATGAAAGTGATGCTGGTTGCTAAGGGAAGGCAACTTGATTCTGTGGGAAGGGCTGTAGC TGATCCATCCGTTGTCTAGATTTGAGTATGAGCACAGTGGAAGAGGATTCTGACACAGTA ACAGTAGAAACTGTGAACTCTGTGACTTTGACTCAGGACACAGAAGGGAATCTCATTCTT CACTGCCCTCAGAATGAAGCGGATGAAATAGACTCAGAAGATAGTATTGAACCTCCACAT AAAAGGCTTTGTTTGTCCTCTGAGGATGATCAGAGTATTGATGATTCTACTCCTTGCATA TCAGTTGTTGCACTTCCACTTTCAGAAAATGATCAGAGCTTTGAAGTGACCATGACTGCG ACCACAGAAGTAGCAGATGATGAGGTTACTGAGGGGACTGTGACACAGATACAGATTTTG CAGAATGAGCAACTAGATGAAATATCTCCCTTGGGTAACGAGGAAGTTTCAGCAGTTAGC CAAGCATGGTTTACAACTAAAGAAGATAAGGATTCTCTGACTAATAAAGGACATANATGG AAGCAGGGGATGTGGTCCAAGGAAGAAATTGATATTTTGATGAAAATATTGAACGCTATC TTAAGGCACGCGNATAAAAGAGCTACAGAAATCATCTTTGAGATGTCANAAGACGAAGAA NAGATTCTACAGGATATAGCATGGGGTCTGAACCGGCCTTTGNTTGCAGTTATANAANAA GTGCTCGCATGTTGATGACAGAACCATGTGGGAAATATACC >OriGene 3' read for NM_021145 unedited
GTCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAACAAATATTCT TTTATTTCTGTTAAACTGAATATACAATTGTTCCCTAGGCAACCAACTTTTGCTTATAAC TACAATTTAATTTCACGTTGACAAAACACAGTGAAAAGACAACTTTGTGAAGATCTAATT ACAATAATAAATAAAATAATTTATACAAGGGTTTTTTTTTCTTGACTTTTCTATAGGGGT CATATTCATTAAAAAGCCCAAAAGGCTACCTTTGCCTTAACCCTTCTGTAGTACAGGAAT GATTCTTAAATTTGTTTCCTTTTGTTATAAAAGCAAATATTGTTTTTTTAAAATAGCCTG AGATGAGAGGTTATATTGTACCCCACCAGCTAACACACTAAGTGGATGACAAACTATTCT CTCGGTAATTTATATAGCAAAACATCTAATAAATGGTCATGGTATCAAGGATAGGTAACA TTACTTCCTTCCTCATTAAGTTTTACTTCAAAGTGCTAACTTTGTAAACTAATGACAGTG GTTTCTGAGGGGGTGAAAACTGCTTAGATTCTGGCGGGTTTTGTTACTATGCTTATCCAT ATTCCCTTTTAAAGTAACAAAAAACCTGTAGAGAATTTTAACTTTTAATGCTTTCCTGTT TACCTGGCTAAACCAGCTCAACTGCCCCCCATGGGTTAACCAAATGTACACCACAAAACC CCCCCTTACGCCTCTAACTTGGAATTCTGTCCACATATCAATCTAAACCTTTTCGAACAC CACCAGATCCCCCGTAAAGCCTCTCACCCTTTTTAGAACCTTGTCCACAAAACCCTTTCG ACCTCAACCCACCCTCTAGAGACCACCACCCTCTCTCTCTTCCTTACAACACCTCTCTTC CCTACCCACCCACCCTTCCGTCTCATCACACCCTCTCTGGCTAACTACG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021145 |
| Insert Size | 3870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021145.2, NP_066968.2 |
| RefSeq Size | 4052 bp |
| RefSeq ORF | 2283 bp |
| Locus ID | 9988 |
| UniProt ID | Q9Y222 |
| Domains | myb_DNA-binding |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (1) encodes the longer isoform (a, also known as DMP1alpha). Variants 1 and 2 encode the same isoform. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209791 | DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 3,990.00 |
|
| RC209791L1 | Lenti-ORF clone of DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 5,890.00 |
|
| RC209791L2 | Lenti-ORF clone of DMTF1 (mGFP-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 5,890.00 |
|
| RC209791L3 | Lenti-ORF clone of DMTF1 (Myc-DDK-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 5,890.00 |
|
| RC209791L4 | Lenti-ORF clone of DMTF1 (mGFP-tagged)-Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 5,890.00 |
|
| RG209791 | DMTF1 (tGFP-tagged) - Human cyclin D binding myb-like transcription factor 1 (DMTF1), transcript variant 1 |
CNY 4,370.00 |
