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SCYL2 (NM_017988) Human Untagged Clone
CAT＃: SC113782
SCYL2 (untagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2)
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMC4; AMCNACC; CVAK104 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC113782 sequence for NM_017988 edited (data generated by NextGen Sequencing)
ATGGAGTCCATGCTTAATAAATTGAAGAGTACTGTTACAAAAGTAACAGCTGATGTCACT AGTGCTGTAATGGGAAATCCTGTCACTAGAGAATTTGATGTTGGTCGACACATTGCCAGT GGTGGCAATGGGCTAGCTTGGAAGATTTTTAATGGCACAAAAAAGTCAACAAAGCAGGAA GTGGCAGTTTTTGTCTTTGATAAAAAACTGATTGACAAGTATCAAAAATTTGAAAAGGAT CAAATCATTGATTCTCTAAAACGAGGAGTCCAACAGTTAACTCGGCTTCGACACCCTCGA CTTCTTACTGTCCAGCATCCTTTAGAAGAATCCAGGGATTGCTTGGCATTTTGTACAGAA CCAGTTTTTGCCAGTTTAGCCAATGTTCTTGGTAACTGGGAAAATCTACCTTCCCCTATA TCTCCAGACATTAAGGATTATAAACTTTATGATGTAGAAACCAAATATGGTTTGCTTCAG GTTTCTGAAGGATTGTCATTCTTGCATAGCAGTGTGAAAATGGTGCATGGAAATATCACT CCTGAAAATATAATTTTGAATAAAAGTGGAGCCTGGAAAATAATGGGTTTTGATTTTTGT GTATCATCAACCAATCCTTCTGAACAAGAGCCTAAATTTCCTTGTAAAGAATGGGACCCA AATTTACCTTCATTGTGTCTTCCAAATCCTGAATATTTGGCTCCTGAATACATACTTTCT GTGAGCTGTGAAACAGCCAGTGATATGTATTCTTTAGGAACTGTTATGTATGCTGTATTT AATAAAGGGAAACCTATATTTGAAGTCAACAAGCAAGATATTTACAAGAGTTTCAGTAGG CAGTTGGATCAGTTGAGTCGTTTAGGATCTAGTTCACTTACAAATATACCTGAGGAAGTT CGTGAACATGTAAAGCTACTGTTAAATGTAACTCCGACTGTAAGACCAGATGCAGATCAA ATGACAAAGATTCCCTTCTTTGATGATGTTGGTGCAGTAACACTGCAATATTTTGATACC TTATTCCAAAGAGATAATCTTCAGAAATCACAGTTTTTCAAAGGACTGCCAAAGGTTCTA CCAAAACTGCCCAAGCGTGTCATTGTGCAGAGAATTTTGCCTTGTTTGACTTCAGAATTT GTAAACCCTGACATGGTACCTTTTGTTTTGCCCAATGTTYTACTTATTGCTGAGGAATGC ACCAAAGAAGAATATGTCAAATTAATTCTTCCTGAACTTGGCCCTGTGTTTAAGCAGCAG GAGCCAATCCAGATTTTGTTAATTTTCCTACAAAAAATGGATTTGCTACTAACCAAAACC CCTCCTGATGAGATAAAGAACAGTGTTCTACCCATGGTTTACAGAGCACTAGAAGCTCCT TCCATTCAGATCCAGGAGCTCTGTCTAAACATCATTCCAACCTTTGCAAATCTTATAGAC TACCCATCCATGAAAAACGCTTTGATACCAAGAATTAAAAATGCTTGTCTACAAACATCT TCCCTTGCGGTTCGTGTAAATTCATTAGTGTGCTTAGGAAAGATTTTGGAATACTTGGAT AAGTGGTTTGTACTTGATGATATCCTACCCTTCTTACAACAAATTCCATCCAAGGAACCT GCGGTCCTCATGGGAATTTTAGGTATTTACAAATGTACTTTTACTCATAAGAAGTTGGGA ATCACCAAAGAGCAGCTGGCCGGAAAAGTGTTGCCTCATCTTATTCCCCTGAGTATTGAA AACAATCTTAATCTTAATCAGTTCAATTCTTTCATTTCCGTCATAAAAGAAATGCTTAAT AGATTGGAGTCTGAACATAAGACTAAACTGGAGCAACTTCATATAATGCAAGAACAGCAG AAATCTTTGGATATAGGAAATCAAATGAATGTTTCTGAGGAGATGAAAGTTACAAATATT GGGAATCAGCAAATTGACAAAGTTTTTAACAACATTGGAGCAGACCTTCTGACTGGCAGT GAGTCCGAAAATAAAGAGGACGGGTTACAGAATAAACATAAAAGAGCATCACTTACACTT GAAGAAAAACAAAAATTAGCAAAAGAACAAGAGCAGGCACAGAAGCTGAAAAGCCAGCAG CCTCTTAAACCCCAAGTGCACACACCTGTTGCTACTGTTAAACAGACTAAGGACTTGACA GACACACTGATGGATAATATGTCATCCTTGACCAGCCTTTCTGTTAGTACCCCTAAATCT TCTGCTTCAAGTACTTTCACTTCTGTTCCTTCCATGGGCATTGGTATGATGTTTTCTACA CCAACTGATAATACAAAGAGAAATTTGACAAATGGCCTAAATGCCAATATGGGCTTTCAG ACTTCAGGATTCAACATGCCCGTTAATACAAACCAGAACTTCTACAGTAGTCCAAGCACA GTTGGAGTGACCAAGATGACTCTGGGAACACCTCCCACTTTGCCAAACTTCAATGCTTTG AGTGTTCCTCCTGCTGGTGCAAAGCAGACCCAACAAAGACCCACAGATATGTCTGCCCTT AATAATCTCTTTGGCCCTCAGAAACCCAAAGTTAGCATGAACCAGTTATCACAACAGAAA CCAAATCAGTGGCTTAATCAGTTTGTACCTCCTCAAGGTTCTCCAACTATGGGCAGTTCA GTAATGGGGACACAGATGAACGTGATAGGACAATCTGCTTTTGGTATGCAGGGTAATCCT TTCTTTAACCCACAGAACTTTGCACAGCCACCAACTACTATGACCAATAGCAGTTCAGCT AGCAATGATTTAAAAGATCTTTTTGGGTGA Clone variation with respect to NM_017988.4 1180 c=>y >OriGene 5' read for NM_017988 unedited
CTATAGGGGCGGCCGCGATTCGGCACGAGGCCCCTCCCCACCCCTTTCCTTCTAGCTCCG ACGTTTGCGGCCGCGGGGGCGGCGGAGGATATGGAGTAAAGCCAGAGTCAGTGGCCAGGC ACGAAGGCAGAGCAGGAACAGCCAGGAGGCGTTTATTAGGGGGGCGGGGGGAAAGAGCCC CAGCACCGCCCCTCCTGGAAGAAGGAAGAGGTAACTATAACTACCCAATATTGCAGCCAT GGAGTCCATGCTTAATAAATTGAAGAGTACTGTTACAAAAGTAACAGCTGATGTCACTAG TGCTGTAATGGGAAATCCTGTCACTAGAGAATTTGATGTTGGTCGACACATTGCCAGTGG TGGCAATGGGCTAGCTTGGAAGATTTTTAATGGCACAAAAAAGTCAACAAAGCAGGAAGT GGCAGTTTTTGTCTTTGATAAAAAACTGATTGACAAGTATCAAAAATTTGAAAAGGATCA AATCATTGATTCTCTAAAACGAGGAGTCCAACAGTTAACTCGGCTTCGACACCCTCGACT TCTTACTGTCCAGCATCCTTTAGAAGAATCCAGGGATTGCTTGGCATTNTGTACAGAACC AGTTTTTGCCAGTTTAGCCAATGTTCTTGGTAACTGGGAAAATCTACCTTCCCCTATATC TCCAGACATTAAGGATTATAAACTTTATGATGTAGAAACCAAATATGGGTTGCTTCAGGT TTCTGAAGGATTGTCATTCTTGCATAGCAGTGTGAAAATGGTGCATGGAAATATCACTCC TGAAAATATATTTTGAATANAGTGGAGCCTGAANATAATGGGGTTTTGATTTTGTGTATC ATCACCAATCCTTCTGACAGAGCCTAAATTCCTTGTAAGAATGGACCAAATTACCTTCAT GGGTCTCCAA >OriGene 3' read for NM_017988 unedited
TCCTCTGCCGCACTCNANAGTTGAGTTTATTTCTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTGAAAGGTTACTCCTAAATATAGTTTAATTCTTACAAATCTTC TTTTGAAAAGGCAATTCATATTTGCTGCACCCCCAAAAGTTTGAATTTGAAATGAAATAT GAAGGGAGTAGTCAGGGAAGTCACATCATTTTGCCTTGGCAAATTTCCAAACAAATGGGG CCATCCCTTTTCCTTGTTACGGGGGGAAAAAAGGGTTTTTAAATTTTTCCAAGGGAATGC CAAAAAATCCTTTTCTTTTTGGGGCCAACCCTGCTAAAATATAATTTACAAGGATTAGTT TGCCCTTAAAAGGGTTAAAAACCCTTTTAACCCCATGAAATGAAGGTTAAGTTGAATTTT GGAGTATTTGCTCAGTCTTTGGCCTAAACAATAGTTCATTTGAAAAGTTTGGAAAAAGCA AATAACCGGGAACTTCTCTTTATGCTTATAATTTTCCCACGGGCATCTTAAAGGCCAACA AATCAATCCCGCTTCAAGATTTTTTCCCTTTTAAAATGAAGACTAATGCCTCTTAGACTG GGTCCCATATAGTACTTAAAAGATGAGCTTGGAAGGACCCTCCCCTCATTTTTTAAATAC CCCGAGTTCCCCAGGCAAAAAAAACTTTGGTTTAAAAGTTTTGTTATTCAGAAACCCCGG TTCCTTTTTCTTTTGAAATGGGAAGGGCTGGTCTTAAAAACCGAAAGAGTTGGAAGAGAA AAAACCTCAGCTTAAAAACTCCCTGGTAAAGTCTACACTCTTGCTGCCTGGCAAAAGTTT CTGGCCAAATGTACTTTCCATAAAATCTCCCCCGCCCCTTTTAGAAGGAAACCCCCCCCT GTTGAACCGAAAACCTTCAAAAAAGAAACCTTCCCCAAATTTTAATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017988 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017988.4, NP_060458.3 |
| RefSeq Size | 3818 bp |
| RefSeq ORF | 2790 bp |
| Locus ID | 55681 |
| UniProt ID | Q6P3W7 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (1) encodes isoform 1. Both variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Interferon-Induced SCYL2 Limits Release of HIV-1 by Triggering PP2A-Mediated Dephosphorylation of the Viral Protein Vpu
,Kei Miyakawa, Tatsuya Sawasaki, Satoko Matsunaga, Andrey Tokarev, Gary Quinn, Hirokazu Kimura, Masako Nomaguchi, Akio Adachi, Naoki Yamamoto, John Guatelli, and Akihide Ryo,
Sci. Signal., Oct 2012; 5: ra73.
[SCYL2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209051 | SCYL2 (Myc-DDK-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 6,808.00 |
|
| RC209051L1 | Lenti-ORF clone of SCYL2 (Myc-DDK-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 9,030.00 |
|
| RC209051L2 | Lenti-ORF clone of SCYL2 (mGFP-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 9,030.00 |
|
| RC209051L3 | Lenti-ORF clone of SCYL2 (Myc-DDK-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 9,030.00 |
|
| RC209051L4 | Lenti-ORF clone of SCYL2 (mGFP-tagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 9,030.00 |
|
| RG209051 | SCYL2 (tGFP-tagged) - Human SCY1-like 2 (S. cerevisiae) (SCYL2) |
CNY 7,890.00 |
