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RTEL1 (NM_016434) Human Untagged Clone
CAT＃: SC304421
RTEL1 (untagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1
CNY 23,560.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_016434, the custom clone sequence may differ by one or more nucleotides
ATGCCCAAGATAGTCCTGAATGGTGTGACCGTAGACTTCCCTTTCCAGCCCTACAAATGC CAACAGGAGTACATGACCAAGGTCCTGGAATGTCTGCAGCAGAAGGTGAATGGCATCCTG GAGAGCCCTACGGGTACAGGGAAGACGCTGTGCCTGCTGTGCACCACGCTGGCCTGGCGA GAACACCTCCGAGACGGCATCTCTGCCCGCAAGATTGCCGAGAGGGCGCAAGGAGAGCTT TTCCCGGATCGGGCCTTGTCATCCTGGGGCAACGCTGCTGCTGCTGCTGGAGACCCCATA GCTTGCTACACGGACATCCCAAAGATTATTTACGCCTCCAGGACCCACTCGCAACTCACA CAGGTCATCAACGAGCTTCGGAACACCTCCTACCGGCCTAAGGTGTGTGTGCTGGGCTCC CGGGAGCAGCTGTGCATCCATCCTGAGGTGAAGAAACAAGAGAGTAACCATCTACAGATC CACTTGTGCCGTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAACGTAGAAGAA AAAAGCCTGGAGCAGGAGCTGGCCAGCCCCATCCTGGACATTGAGGACTTGGTCAAGAGC GGAAGCAAGCACAGGGTGTGCCCTTACTACCTGTCCCGGAACCTGAAGCAGCAAGCCGAC ATCATATTCATGCCGTACAATTACTTGTTGGATGCCAAGAGCCGCAGAGCACACAACATT GACCTGAAGGGGACAGTCGTGATCTTTGACGAAGCTCACAACGTGGAGAAGATGTGTGAA GAATCGGCATCCTTTGACCTGACTCCCCATGACCTGGCTTCAGGACTGGACGTCATAGAC CAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAGGGTGAGCCCCACCCGGAGTTCAGC GCGGACTCCCCCAGCCCAGGGCTGAACATGGAGCTGGAAGACATTGCAAAGCTGAAGATG ATCCTGCTGCGCCTGGAGGGGGCCATCGATGCTGTTGAGCTGCCTGGAGACGACAGCGGT GTCACCAAGCCAGGGAGCTACATCTTTGAGCTGTTTGCTGAAGCCCAGATCACGTTTCAG ACCAAGGGCTGCATCCTGGACTCGCTGGACCAGATCATCCAGCACCTGGCAGGACGTGCT GGAGTGTTCACCAACACGGCCGGACTGCAGAAGCTGGCGGACATTATCCAGATTGTGTTC AGTGTGGACCCCTCCGAGGGCAGCCCTGGTTCCCCAGCAGGGCTGGGGGCCTTACAGTCC TATAAGGTGCACATCCATCCTGATGCTGGTCACCGGAGGACGGCTCAGCGGTCTGATGCC TGGAGCACCACTGCAGCCAGAAAGCGAGGGAAGGTGCTGAGCTACTGGTGCTTCAGTCCC GGCCACAGCATGCACGAGCTGGTCCGCCAGGGCGTCCGCTCCCTCATCCTTACCAGCGGC ACGCTGGCCCCGGTGTCCTCCTTTGCTCTGGAGATGCAGATCCCTTTCCCAGTCTGCCTG GAGAACCCACACATCATCGACAAGCACCAGATCTGGGTGGGGGTCGTCCCCAGAGGCCCC GATGGAGCCCAGTTGAGCTCCGCGTTTGACAGACGGTTTTCCGAGGAGTGCTTATCCTCC CTGGGGAAGGCTCTGGGCAACATCGCCCGCGTGGTGCCCTATGGGCTCCTGATCTTCTTC CCTTCCTATCCTGTCATGGAGAAGAGCCTGGAGTTCTGGCGGGCCCGCGACTTGGCCAGG AAGATGGAGGCGCTGAAGCCGCTGTTTGTGGAGCCCAGGAGCAAAGGCAGCTTCTCCGAG ACCATCAGTGCTTACTATGCAAGGGTTGCCGCCCCTGGGTCCACCGGCGCCACCTTCCTG GCGGTCTGCCGGGGCAAGGCCAGCGAGGGGCTGGACTTCTCAGACACGAATGGCCGTGGT GTGATTGTCACGGGCCTCCCGTACCCCCCACGCATGGACCCCCGGGTTGTCCTCAAGATG CAGTTCCTGGATGAGATGAAGGGCCAGGGTGGGGCTGGGGGCCAGTTCCTCTCTGGGCAG GAGTGGTACCGGCAGCAGGCGTCCAGGGCTGTGAACCAGGCCATCGGGCGAGTGATCCGG CACCGCCAGGACTACGGAGCTGTCTTCCTCTGTGACCACAGGTTCGCCTTTGCCGACGCA AGAGCCCAACTGCCCTCCTGGGTGCGTCCCCACGTCAGGGTGTATGACAACTTTGGCCAT GTCATCCGAGACGTGGCCCAGTTCTTCCGTGTTGCCGAGCGAACTATGCCAGCGCCGGCC CCCCGGGCTACAGCACCCAGTGTGCGTGGAGAAGATGCTGTCAGCGAGGCCAAGTCGCCT GGCCCCTTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACCTGCATGTCCCCAGCCTGAAG CAGAGGTCCTCAGGGTCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTGTGTGGAGTAT GAGCAGGAGCCAGTTCCTGCCCGGCAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCAC AGCGAACAGCGGGCGGGGAGCCCTGGCGAGGAGCAGGCCCACAGCTGCTCCACCCTGTCC CTCCTGTCTGAGAAGAGGCCGGCAGAAGAACCGCGAGGAGGGAGGAAGAAGATCCGGCTG GTCAGCCACCCGGAGGAGCCCGTGGCTGGTGCACAGACGGACAGGGCCAAGCTCTTCATG GTGGCCGTGAAGCAGGAGTTGAGCCAAGCCAACTTTGCCACCTTCACCCAGGCCCTGCAG GACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCTGTCTCGGCCCCCTCTTTGCT GAGGACCCCAAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCGGCCCCACCAT AAGCAGCAGTTTGAGGAGGTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCT GAGCACAGCATTCCCCGAAGGCAGCGGGCACAGCCGGTCCTGGACCCCACTGGAAGAACG GCGCCGGATCCCAAGCTGACCGTGTCCACGGCTGCAGCCCAGCAGCTGGACCCCCAAGAG CACCTGAACCAGGGCAGGCCCCACCTGTCGCCCAGGCCACCCCCAACAGGAGACCCTGGC AGCCAACCACAGTGGGGGTCTGGAGTGCCCAGAGCAGGGAAGCAGGGCCAGCACGCCGTG AGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCGCGGGCTGTAGCCAACTCTTG GCAGCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGCTGTGTTGGCC GCCCTGACCACTGCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTG CGTCCACACCACAAGCAGCGCTTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTAC CCGGGCATGGAGCCACCGGGACCCCAGGAGGAGAGGCTTGCCGTGCCTCCTGTGCTTACC CACAGGGCTCCCCAACCAGGCCCCTCACGGTCCGAGAAGACCGGGAAGACCCAGAGCAAG ATCTCGTCCTTCCTTAGACAGAGGCCAGCAGGGACTGTGGGGGCGGGCGGTGAGGATGCA GGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCTGCAGCATCTGAGTGGGGCCTCTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_016434 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_016434.2, NP_057518.1 |
| RefSeq Size | 4462 bp |
| RefSeq ORF | 3660 bp |
| Locus ID | 51750 |
| UniProt ID | Q9NZ71 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region that results in a translational frameshift, compared to variant 3. The resulting protein (isoform 1) has a distinct C-terminus and is shorter than isoform 3. |
Documents
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214507 | RTEL1 (Myc-DDK-tagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1 |
CNY 12,160.00 |
|
| RC214507L3 | Lenti-ORF clone of RTEL1 (Myc-DDK-tagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1 |
CNY 14,060.00 |
|
| RC214507L4 | Lenti-ORF clone of RTEL1 (mGFP-tagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1 |
CNY 14,060.00 |
|
| RG214507 | RTEL1 (tGFP-tagged) - Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1 |
CNY 13,400.00 |
