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DENN (MADD) (NM_003682) Human Untagged Clone
CAT＃: SC309758
MADD (untagged)-Human MAP-kinase activating death domain (MADD), transcript variant 4
CNY 31,830.00
货期*
4周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEEAH; DENN; IG20; NEDDISH; RAB3GEP; RabGEF |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309758 representing NM_003682.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGTGCAAAAGAAGAAGTTCTGTCCTCGGTTACTTGACTATCTAGTGATCGTAGGGGCCAGGCACCCG AGCAGTGATAGCGTGGCCCAGACTCCTGAATTGCTACGGCGATACCCCTTGGAGGATCACACTGAGTTT CCCCTGCCCCCAGATGTAGTGTTCTTCTGCCAGCCCGAGGGCTGCCTGAGCGTGCGGCAGCGGCGCATG AGCCTTCGGGATGATACCTCTTTTGTCTTCACCCTCACTGACAAGGACACTGGAGTCACGCGATATGGC ATCTGTGTTAACTTCTACCGCTCCTTCCAAAAGCGAATCTCTAAGGAGAAGGGGGAAGGTGGGGCAGGG TCCCGTGGGAAGGAAGGAACCCATGCCACCTGTGCCTCAGAAGAGGGTGGCACTGAGAGCTCAGAGAGT GGCTCATCCCTGCAGCCTCTCAGTGCTGACTCTACCCCTGATGTGAACCAGTCTCCTCGGGGCAAACGC CGGGCCAAGGCGGGGAGCCGCTCCCGCAACAGTACTCTCACGTCCCTGTGCGTGCTCAGCCACTACCCT TTCTTCTCCACCTTCCGAGAGTGTTTGTATACTCTCAAGCGCCTGGTGGACTGCTGTAGTGAGCGCCTT CTGGGCAAGAAACTGGGCATCCCTCGAGGCGTACAAAGGGACACCATGTGGCGGATCTTTACTGGATCG CTGCTGGTAGAGGAGAAGTCAAGTGCCCTTCTGCATGACCTTCGAGAGATTGAGGCCTGGATCTATCGA TTGCTGCGCTCCCCAGTACCCGTCTCTGGGCAGAAGCGAGTAGACATCGAGGTCCTACCCCAAGAGCTC CAGCCAGCTCTGACCTTTGCTCTTCCAGACCCATCTCGATTCACCCTAGTGGATTTCCCACTGCACCTT CCCTTGGAACTTCTAGGTGTGGACGCCTGTCTCCAGGTGCTAACCTGCATTCTGTTAGAGCACAAGGTG GTGCTACAGTCCCGAGACTACAATGCACTCTCCATGTCTGTGATGGCATTCGTGGCAATGATCTACCCA CTGGAGTATATGTTTCCTGTCATCCCGCTGCTACCCACCTGCATGGCATCAGCAGAGCAGCTGCTGTTG GCTCCAACCCCGTACATCATTGGGGTTCCTGCCAGCTTCTTCCTCTACAAACTGGACTTCAAAATGCCT GATGATGTATGGCTAGTGGATCTGGACAGCAATAGGGTGATTGCCCCCACCAATGCAGAAGTGCTGCCT ATCCTGCCAGAACCAGAATCACTAGAGCTGAAAAAGCATTTAAAGCAGGCCTTGGCCAGCATGAGTCTC AACACCCAGCCCATCCTCAATCTGGAGAAATTTCATGAGGGCCAGGAGATCCCCCTTCTCTTGGGAAGG CCTTCTAATGACCTGCAGTCCACACCGTCCACTGAATTCAACCCACTCATCTATGGCAATGATGTGGAT TCTGTGGATGTTGCAACCAGGGTTGCCATGGTACGGTTCTTCAATTCCGCCAACGTGCTGCAGGGATTT CAGATGCACACGCGTACCCTGCGCCTCTTTCCTCGGCCTGTGGTAGCTTTTCAAGCTGGCTCCTTTCTA GCCTCACGTCCCCGGCAGACTCCTTTTGCCGAGAAATTGGCCAGGACTCAGGCTGTGGAGTACTTTGGG GAATGGATCCTTAACCCCACCAACTATGCCTTTCAGCGAATTCACAACAATATGTTTGATCCAGCCCTG ATTGGTGACAAGCCAAAGTGGTATGCTCATCAGCTGCAGCCTATCCACTATCGCGTCTATGACAGCAAT TCCCAGCTGGCTGAGGCCCTGAGTGTACCACCAGAGCGGGACTCTGACTCCGAACCTACTGATGATAGT GGCAGTGATAGTATGGATTATGACGATTCAAGCTCTTCTTACTCCTCCCTTGGTGACTTTGTCAGTGAA ATGATGAAATGTGACATTAATGGTGATACTCCCAATGTGGACCCTCTGACACATGCAGCACTGGGGGAT GCCAGCGAGGTGGAGATTGACGAGCTGCAGAATCAGAAGGAAGCAGAAGAGCCTGGCCCAGACAGTGAG AACTCTCAGGAAAACCCCCCACTGCGCTCCAGCTCTAGCACCACAGCCAGCAGCAGCCCCAGCACTGTC ATCCACGGAGCCAACTCTGAACCTGCTGACTCTACGGAGATGGATGATAAGGCAGCAGTAGGCGTCTCC AAGCCCCTCCCTTCCGTGCCTCCCAGCATTGGCAAATCGAACGTGGACAGACGTCAGGCAGAAATTGGA GAGGGGTCAGTGCGCCGGCGAATCTATGACAATCCATACTTCGAGCCCCAATATGGCTTTCCCCCTGAG GAAGATGAGGATGAGCAGGGGGAAAGTTACACTCCCCGATTCAGCCAACATGTCAGTGGCAATCGGGCT CAAAAGCTGCTGCGGCCCAACAGCTTGAGACTGGCAAGTGACTCAGATGCAGAGTCAGACTCTCGGGCA AGCTCTCCCAACTCCACCGTCTCCAACACCAGCACCGAGGGCTTCGGGGGCATCATGTCTTTTGCCAGC AGCCTCTATCGGAACCACAGTACCAGCTTCAGTCTTTCAAACCTCACACTGCCCACCAAAGGTGCCCGA GAGAAGGCCACGCCCTTCCCCAGTCTGAAAGTATTTGGGCTAAATACTCTAATGGAGATTGTTACTGAA GCCGGCCCCGGGAGTGGTGAAGGAAACAGGAGGGCGTTAGTGGATCAGAAGTCATCTGTCATTAAACAC AGCCCAACAGTGAAAAGAGAACCTCCATCACCCCAGGGTCGATCCAGCAATTCTAGTGAGAACCAGCAG TTCCTGAAGGAGGTGGTGCACAGCGTGCTGGACGGCCAGGGAGTTGGCTGGCTCAACATGAAAAAGGTG CGCCGGCTGCTGGAGAGCGAGCAGCTGCGAGTCTTTGTCCTGAGCAAGCTGAACCGCATGGTGCAGTCA GAGGACGATGCCCGGCAGGACATCATCCCGGATGTGGAGATCAGTCGGAAGGTGTACAAGGGAATGTTA GACCTCCTCAAGTGTACAGTCCTCAGCTTGGAGCAGTCCTATGCCCACGCGGGTCTGGGTGGCATGGCC AGCATCTTTGGGCTTTTGGAGATTGCCCAGACCCACTACTATAGTAAAGAACCAGACAAGCGGAAGAGA AGTCCAACAGAAAGTGTAAATACCCCAGTTGGCAAGGATCCTGGCCTAGCTGGGCGGGGGGACCCAAAG GCTATGGCACAACTGAGAGTTCCACAACTGGGACCTCGGGCACCAAGTGCCACAGGAAAGGGTCCTAAG GAACTGGACACCAGAAGTTTAAAGGAAGAAAATTTTATAGCATCTATTGAATTGTGGAACAAGCACCAG GAAGTGAAAAAGCAAAAAGCTTTGGAAAAACAGAGGCCTGAAGTAATCAAACCTGTCTTTGACCTTGGT GAGACAGAGGAGAAAAAGTCCCAGATCAGCGCAGACAGTGGTGTGAGCCTGACGTCTAGTTCCCAGAGG ACTGATCAAGACTCTGTCATCGGCGTGAGTCCAGCTGTTATGATCCGCAGCTCAAGTCAGGATTCTGAA GTTAGCACCGTGGTGAGTAATAGCTCTGGAGAGACCCTTGGAGCTGACAGTGACTTGAGCAGCAATGCA GGTGATGGACCAGGTGGCGAGGGCAGTGTTCACCTGGCAAGCTCTCGGGGCACTTTGTCTGATAGTGAA ATTGAGACCAACTCTGCCACAAGCACCATCTTTGGTAAAGCCCACAGCTTGAAGCCAAGCATAAAGGAG AAGCTGGCAGGCAGCCCCATTCGTACTTCTGAAGATGTGAGCCAGCGAGTCTATCTCTATGAGGGACTC CTAGGAAGGGACAAAGGATCCATGTGGGACCAGTTAGAGGATGCAGCTATGGAGACCTTTTCTATAAGC AAAGAGCGTTCTACTTTATGGGACCAAATGCAATTCTGGGAAGATGCCTTCTTAGATGCTGTGATGTTG GAGAGAGAAGGGATGGGTATGGACCAGGGTCCCCAGGAAATGATCGACAGGTACCTGTCCCTTGGAGAA CATGACCGGAAGCGCCTGGAAGATGATGAAGATCGCTTGCTGGCCACACTTCTGCACAACCTCATCTCC TACATGCTGCTGATGAAGGTAAATAAGAATGACATCCGCAAGAAGGTGAGGCGCCTAATGGGAAAGTCG CACATTGGGCTTGTGTACAGCCAGCAAATCAATGAGGTGCTTGATCAGCTGGCGAACCTGAATGGACGC GATCTCTCTATCTGGTCCAGTGGCAGCCGGCACATGAAGAAGCAGACATTTGTGGTACATGCAGGGACA GATACAAACGGAGATATCTTTTTCATGGAGGTGTGCGATGACTGTGTGGTGTTGCGTAGTAACATCGGA ACAGTGTATGAGCGCTGGTGGTACGAGAAGCTCATCAACATGACCTACTGTCCCAAGACGAAGGTGTTG TGCTTGTGGCGTAGAAATGGCTCTGAGACCCAGCTCAACAAGTTCTATACTAAAAAGTGTCGGGAGCTG TACTACTGTGTGAAGGACAGCATGGAGCGCGCTGCCGCCCGACAGCAAAGCATCAAACCCGGACCTGAA TTGGGTGGCGAGTTCCCTGTGCAGGACCTGAAGACTGGTGAGGGTGGCCTGCTGCAGGTGACCCTGGAA GGGATCAACCTCAAATTCATGCACAATCAGGTTTTCATAGAGCTGAATCACATTAAAAAGTGCAATACA GTTCGAGGCGTCTTTGTCCTGGAGGAATTTGTTCCTGAAATTAAAGAAGTGGTGAGCCACAAGTACAAG ACACCAATGGCCCACGAAATCTGCTACTCCGTATTATGTCTCTTCTCGTACGTGGCTGCAGTTCATAGC AGTGAGGAAGATCTCAGAACCCCGCCCCGGCCTGTCTCTAGCTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGAT ATCCTGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_003682 |
| Insert Size | 4944 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003682.3 |
| RefSeq Size | 6031 bp |
| RefSeq ORF | 4944 bp |
| Locus ID | 8567 |
| UniProt ID | Q8WXG6 |
| Domains | DENN, dDENN, uDENN |
| Protein Families | Druggable Genome |
| MW | 183.3 kDa |
| Gene Summary | Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (d). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219397 | MADD (Myc-DDK-tagged)-Human MAP-kinase activating death domain (MADD), transcript variant 4 |
CNY 11,272.00 |
|
| RC219397L3 | Lenti ORF clone of Human MAP-kinase activating death domain (MADD), transcript variant 4, Myc-DDK-tagged |
CNY 13,672.00 |
|
| RC219397L4 | Lenti ORF clone of Human MAP-kinase activating death domain (MADD), transcript variant 4, mGFP tagged |
CNY 18,340.00 |
|
| RG219397 | MADD (tGFP-tagged) - Human MAP-kinase activating death domain (MADD), transcript variant 4 |
CNY 18,050.00 |
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