Srf (NM_020493) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208120L1V
- LentiORF®
Lenti ORF particles, Srf (Myc-DDK-tagged) - Mouse serum response factor (Srf), 200ul, >10^7 TU/mL
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CNY 9,595.00
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Specifications
Product Data | |
Product Name | Srf (NM_020493) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AW049942; AW240594 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_020493 |
ORF Size | 1512 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208120).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_020493.2, NP_065239.1 |
RefSeq Size | 4093 bp |
RefSeq ORF | 1515 bp |
Locus ID | 20807 |
Gene Summary | SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (PubMed:24732378). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:12732141, PubMed:19350017, PubMed:24732378). The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics (PubMed:24732378). Required for cardiac differentiation and maturation (PubMed:15169892).[UniProtKB/Swiss-Prot Function] |
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