United States
Germany
Japan
United Kingdom
China
Bbs7 (NM_027810) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210222L4V
- LentiORF®
-
Lenti ORF particles, Bbs7 (GFP-tagged) - Mouse Bardet-Biedl syndrome 7 (human) (Bbs7), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 13,300.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Bbs7 (NM_027810) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 8430406N16Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_027810 |
| ORF Size | 2148 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210222).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_027810.1, NP_082086.1 |
| RefSeq Size | 2598 bp |
| RefSeq ORF | 2148 bp |
| Locus ID | 71492 |
| Gene Summary | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
