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Btla (NM_177584) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226024L3V
- LentiORF®
-
Lenti ORF particles, Btla (Myc-DDK-tagged) - Mouse B and T lymphocyte associated (Btla), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Btla (NM_177584) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | A630002H24 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_177584 |
| ORF Size | 915 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226024).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_177584.3, NP_808252.1 |
| RefSeq Size | 3232 bp |
| RefSeq ORF | 918 bp |
| Locus ID | 208154 |
| Gene Summary | Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).[UniProtKB/Swiss-Prot Function] |
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