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Btla (NM_177584) Mouse Untagged Clone
CAT＃: MC212498
Btla (untagged) - Mouse B and T lymphocyte associated (Btla), transcript variant 2, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | A630002H24 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC212498 representing NM_177584
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGACAGTGCCTGCCATGCTTGGGACTCCTCGGTTATTTAGGGAATTCTTCATCCTCCATCTGGGCC TCTGGAGCATCCTTTGTGAGAAAGCTACTAAGAGGAATGATGAAGAGTGTCCAGTGCAACTTACTATTAC GAGGAATTCCAAACAGTCTGCCAGGACAGGAGAGTTATTTAAAATTCAATGTCCTGTGAAATACTGTGTT CATAGACCTAATGTGACTTGGTGTAAGCACAATGGAACAATCTGTGTACCCCTTGAGGTTAGCCCTCAGC TATACACTAGTTGGGAAGAAAATCAATCAGTTCCGGTTTTTGTTCTCCACTTTAAACCAATACATCTCAG TGATAATGGGTCGTATAGCTGTTCTACAAACTTCAATTCTCAAGTTATTAATAGCCATTCAGTAACCATC CATGTGACAGAAAGGACTCAAAACTCTTCAGAACACCCACTAATAATATCTGACATCCCAGATGCCACCA ATGCCTCAGGACCATCCACCATGGAAGAGAGGCCAGGCAGGACTTGGCTGCTTTACACCTTGCTTCCTTT GGGGGCATTGCTTCTGCTCCTTGCCTGTGTCTGCCTGCTCTGCTTTCTGAAAAGGATCCAAGGGAAAGAA AAGAAGCCTTCTGACTTGGCAGGAAGGGACACTAACCTGGTTGATATTCCAGCCAGTTCCAGGACAAATC ACCAAGCACTGCCATCAGGAACTGGAATTTATGATAATGATCCCTGGTCTAGCATGCAGGATGAATCTGA ATTGACAATTAGCTTGCAATCAGAGAGAAACAACCAGGGCATTGTTTATGCTTCTTTGAACCATTGTGTT ATTGGAAGGAATCCAAGACAGGAAAACAACATGCAGGAGGCACCCACAGAATATGCATCCATTTGTGTGA GAAGTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_177584 |
| Insert Size | 918 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177584.3, NP_808252.1 |
| RefSeq Size | 3232 bp |
| RefSeq ORF | 918 bp |
| Locus ID | 208154 |
| UniProt ID | Q7TSA3 |
| Gene Summary | Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226024 | Btla (tGFP-tagged) - Mouse B and T lymphocyte associated (Btla) transcript variant 2, (10ug) |
CNY 3,330.00 |
|
| MR226024 | Btla (Myc-DDK-tagged) - Mouse B and T lymphocyte associated (Btla), transcript variant 2 |
CNY 3,040.00 |
|
| MR226024L3 | Lenti ORF clone of Btla (Myc-DDK-tagged) - Mouse B and T lymphocyte associated (Btla), transcript variant 2 |
CNY 4,940.00 |
|
| MR226024L4 | Lenti ORF clone of Btla (mGFP-tagged) - Mouse B and T lymphocyte associated (Btla), transcript variant 2 |
CNY 4,940.00 |
