ESE1 (ELF3) (NM_004433) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200631L2V

  • LentiORF®

Lenti ORF particles, ELF3 (mGFP-tagged) - Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name ESE1 (ELF3) (NM_004433) Human Tagged ORF Clone Lentiviral Particle
Synonyms EPR-1; ERT; ESE-1; ESX
Vector pLenti-C-mGFP
ACCN NM_004433
ORF Size 1113 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC200631).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_004433.3
RefSeq Size 3149 bp
RefSeq ORF 1116 bp
Locus ID 1999
Domains ETS, AT_hook, SAM_PNT
Protein Families Transcription Factors
MW 41.5 kDa
Gene Summary Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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