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PSAP (NM_001042466) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC213049L4V
- LentiORF®
-
Lenti ORF particles, PSAP (mGFP-tagged) - Human prosaposin (PSAP), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 9,975.00
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| Product Data | |
| Product Name | PSAP (NM_001042466) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | GLBA; SAP1; SAP2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001042466 |
| ORF Size | 1425 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC213049).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001042466.1 |
| RefSeq Size | 2845 bp |
| RefSeq ORF | 1581 bp |
| Locus ID | 5660 |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysosome |
| MW | 58.1 kDa |
| Gene Summary | This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
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