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PHF8 (NM_015107) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214763L1V
- LentiORF®
-
Lenti ORF particles, PHF8 (Myc-DDK-tagged)-Human PHD finger protein 8 (PHF8), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 11,210.00
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Specifications
| Product Data | |
| Product Name | PHF8 (NM_015107) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | JHDM1F; KDM7B; MRXSSD; ZNF422 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_015107 |
| ORF Size | 3072 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214763).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_015107.1 |
| RefSeq Size | 5776 bp |
| RefSeq ORF | 3075 bp |
| Locus ID | 23133 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 113.7 kDa |
| Gene Summary | The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] |
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