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PTPN13 (NM_006264) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC216670L1V
- LentiORF®
-
Lenti ORF particles, PTPN13 (Myc-DDK tagged) - Human protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 21,660.00
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规格
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Specifications
| Product Data | |
| Product Name | PTPN13 (NM_006264) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_006264 |
| ORF Size | 6852 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC216670).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006264.1 |
| RefSeq Size | 8062 bp |
| RefSeq ORF | 7401 bp |
| Locus ID | 5783 |
| Domains | Y_phosphatase, B41, PDZ, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase |
| MW | 254.51 kDa |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008] |
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