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Flt4 (NM_008029) Mouse Tagged Lenti ORF Clone
CAT＃: MR225313L2
- LentiORF®
Lenti ORF clone of Flt4 (mGFP-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4)
"NM_008029" in other vectors (6)
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CNY 16,392.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | AI323512; Chy; Flt-4; VEGFR-3; VEGFR3 |
| Vector | pLenti-C-mGFP |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225313).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_008029 |
| ORF Size | 4089 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_008029.3, NP_032055.1 |
| RefSeq Size | 5853 bp |
| RefSeq ORF | 4092 bp |
| Locus ID | 14257 |
| UniProt ID | P35917 |
| Gene Summary | Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224341 | Flt4 (untagged) - Mouse FMS-like tyrosine kinase 4 (Flt4), (10ug) |
CNY 17,480.00 |
|
| MG225313 | Flt4 (tGFP-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4), (10ug) |
CNY 15,592.00 |
|
| MR225313 | Flt4 (Myc-DDK-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4) |
CNY 13,992.00 |
|
| MR225313L1 | Lenti ORF clone of Flt4 (Myc-DDK-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4) |
CNY 15,490.00 |
|
| MR225313L3 | Lenti ORF clone of Flt4 (Myc-DDK-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4) |
CNY 15,490.00 |
|
| MR225313L4 | Lenti ORF clone of Flt4 (mGFP-tagged) - Mouse FMS-like tyrosine kinase 4 (Flt4) |
CNY 15,490.00 |
