STAT5A pTyr695/699 Mouse Monoclonal Antibody [Clone ID: 5G4]
CAT#: AM00150PU-N
STAT5A pTyr695/699 mouse monoclonal antibody, clone 5G4, Purified
Need it in bulk or conjugated?
Get a free quote
CNY 5,973.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 5G4 |
Applications | ELISA, IF, IHC, WB |
Recommend Dilution | Western Blot: 0.5 µg/ml for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer. ELISA: 0.05 µg/ml. Immunohistochemistry. Immunocytochemistry. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Synthetic phosphopeptide conjuagted to KLH |
Specificity | This antibody specifically recognizes STAT5A phosphorylated at Tyr 694 and STAT5B phosphorylated at Tyr 699. The antibody does not crossreact with the non-phosphorylated form of STAT5 nor with unrelated tyrosine-phosphorylated proteins. |
Formulation | PBS/0.09% Na-Azide/PEG and Sucrose/50% Glycerol State: Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | Size exclusion chromatography |
Conjugation | Unconjugated |
Storage Condition | Store the antibody (Aliquote and freeze in liquid nitrogen) at -20°C. Avoid repeated freezing and thawing. Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months. |
Gene Name | signal transducer and activator of transcription 5A |
Database Link | |
Background | The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. STAT5 is activated in response to prolactine, growth hormone, GM-CSF, and IL-2. |
Synonyms | STAT-5, STAT-5A, Mammary gland factor, MGF |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...