alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: 131-12210 (TB-4B2-10)]

Specifications

Product Data
Clone Name	131-12210 (TB-4B2-10)
Applications	ELISA, IHC
Recommend Dilution	Immunohistochemistry. ELISA. Recommended pair for sandwich immunoassay: Capture: AM00787PU-N Detection: AM00786PU-N
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	AFP prepared from human placenta
Specificity	This antibody recognizes Alpha Fetoprotein (AFP).
Formulation	10mM Phosphate, pH 7.2 containing 150mM Sodium Chloride State: Purified State: Liquid purified IgG fraction (0.2µm filtered) Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	alpha fetoprotein
Database Link	Entrez Gene 174 Human UniProt ID P02771
Background	Alpha fetoprotein is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults. Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down’s syndrome.
Synonyms	Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
Note	Centrifuge before opening to ensure complete recovery of vial contents.
Reference Data

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