Influenza A (Nucleoprotein) Mouse Monoclonal Antibody [Clone ID: B247M]

Specifications

Product Data
Clone Name	B247M
Applications	ELISA, WB
Recommend Dilution	Suitable for use in ELISA and Western Blot. Recommended pair for Sandwich Immunoassay: Capture/Detection: AM00929PU-N/AM00930PU-N
Reactivity	Influenza A Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Influenza virus type A (H1N1). Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/c mice.
Specificity	This antibody reacts with Influenza Virus type A Nucleoprotein. Does not crossreact with Influenza Virus type B Nucleoprotein.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction (>90% pure by SDS-PAGE).
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Background	The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
Synonyms	Influenza A Virus, Seasonal Flu
Reference Data

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