Cortisol Mouse Monoclonal Antibody [Clone ID: BGN/C53]

Specifications

Product Data
Clone Name	BGN/C53
Applications	ELISA
Recommend Dilution	ELISA: 1/500-1/5000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Corticosterone conjugated to Bovine Serum Albumin.
Specificity	This antibody recognises the glucocorticoid hormone cortisol, produced in the adrenal cortex and involved in responses to stress. Cross reactivity: Cortisol: 100% Corticosterone: 50% Prednisolone: 15% 11-Desoxycortisol: 0.1% Cortisone: < 0.1% 17-a-OH Progesterone: < 0.1%
Formulation	PBS containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing.
Background	Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Synonyms	Hydrocortisone
Note	Cortisol CAS Number: 50-23-7
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.