PDPN Mouse Monoclonal Antibody [Clone ID: 4D5aE5E6]

Specifications

Product Data
Clone Name	4D5aE5E6
Applications	IHC
Recommend Dilution	Immunohistochemistry on frozen sections: 0.75µg/ml - 2µg/ml. Immunohistochemistry on paraffin sections: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Normal lung
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	ORF Human podoplanin ectodomain expressed in E.coli Page 1 of 3.
Specificity	This antibody recognizes Human Podoplanin (gp36).
Formulation	PBS containing 0,09% Sodium Azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	podoplanin
Database Link	Entrez Gene 10630 Human UniProt ID Q86YL7
Background	Podoplanin a 36kDa type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore This antibody is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.
Synonyms	Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
Reference Data

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