CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: DJ130c]

Specifications

Product Data
Clone Name	DJ130c
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of Neat - 1/10 diluted antibody to label 1x106 cells in 100 µl.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises CD16, a 50-65kD cell surface molecule. DJ130c recognises all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognises an epitope in the first membrane-distal domain of CD16 and recognises both CD16A and CD16B.
Formulation	PBS, pH 7.4 Label: Biotin State: Liquid purified IgG fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Biotin
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Fc fragment of IgG receptor IIIa
Database Link	Entrez Gene 2214 Human UniProt ID P08637
Background	CD16 is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2.
Synonyms	FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2
Reference Data

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