BMP7 Mouse Monoclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA: In a sandwich ELISA (assuming 100 µl/well), when used as a capture antibody at a concentration of 2-4 µg/ml, this BMP7 antibody will detect at least 0.1 ng/well of recombinant human BMP-7/OP-1 when used with Biotin conjugated anti-BMP-7/OP-1 antibody (cat. AP01113BT) as the detection antibody at a concentration of at least 0.5 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Highly pure (>98%) recombinant Human BMP-7/OP-1
Specificity	This antibody detects BMP7.
Formulation	PBS without preservatives State: Azide Free State: Lyophilized (sterile filtered) purified IgG fraction
Reconstitution Method	Restore in sterile water to a concentration of 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	The lyophilized antibody is stable at room temperature for one month or at -20°C for longer. Following reconstitution it is stable at 2-8°C for six weeks. Avoid repeated freezing and thawing.
Gene Name	bone morphogenetic protein 7
Database Link	Entrez Gene 655 Human UniProt ID P18075
Background	Bone Morphogenetic Protein 7 (BMP7), also known as osteogenic protein 1 (OP1), is produced from a DNA sequence encoding the human BMP2 signal peptide and human BMP2 propeptide (amino acid residues 1 to 282) fused to the human BMP7 mature subunit (amino acid residues 293 to 431). Mature human BMP7, generated after the proteolytic removal of the signal peptide and the propeptide, is a disulfide linked homodimeric protein, comprised of two 139 amino acid residue subunits. Bone Morphogenetic Proteins (BMP) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species.
Synonyms	BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1
Reference Data

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