Macrophage Inflammatory Protein 3 beta (CCL19) Mouse Monoclonal Antibody
CAT#: AM01367PU-N
Macrophage Inflammatory Protein 3 beta (CCL19) mouse monoclonal antibody, Azide Free
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CNY 3,630.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | ELISA |
Recommend Dilution | ELISA: In a sandwich ELISA (assuming 100 µl/well), a concentration of 2-3 µg/ml of this antibody will detect at least 0.2 ng/well of recombinant human MIP-3-beta when used with biotinylated antigen affinity purified anti-human MIP-3-beta as the detection antibody at a concentration of at least 0.5 µg/ml. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant human MIP-3-beta |
Specificity | This antibody detects MIP-3 beta. |
Formulation | State: Azide Free State: Lyophilized IgG fraction |
Reconstitution Method | Restore in sterile water to a concentration of 1 mg/ml. |
Purification | Protein A chromatography |
Conjugation | Unconjugated |
Storage Condition | The lyophilized antibody is stable at room temperature for one month or at -20 °C for longer. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing. |
Gene Name | C-C motif chemokine ligand 19 |
Database Link | |
Background | MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30% aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13. |
Synonyms | C-C motif chemokine 19, CCL-19, ELC, MIP3B, MIP-3 beta, Small-inducible cytokine A19, SCYA19, Exodus-3 |
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